Glucagons and Glucagon-Like Peptides (GLP-1 / GLP-2)

Lixisenatide

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CAT#
10-101-133
Synonyms/Alias
ZP-10(Des-Pro³⁸)-Exendin-4(-Lys)₆ amide
CAS No.
320367-13-3
Sequence
H-His-Gly-Glu-Gly-Thr-PheThr-Ser-Asp-Leu-Ser-LysGln-Met-Glu-Glu-Glu-AlaVal-Arg-Leu-Phe-Ile-GluTrp-Leu-Lys-Asn-Gly-GlyPro-Ser-Ser-Gly-Ala-ProPro-Ser-Lys-Lys-Lys-LysLys-Lys-NH2
M.W/Mr.
4858.53
Molecular Formula
C215H347N61O65S
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Lixisenatide is a potent GLP-1 receptor agonist.
Description
GLP-1 is a naturally-occurring peptide that is released within minutes of eating a meal. It is known to suppress glucagon secretion from pancreatic alpha cells and stimulate insulin secretion by pancreatic beta cells. GLP-1 receptor agonists are in development as an add-on treatment for type 2 diabetes.
Areas of Interest
Diabetes II
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