Glucagon-like peptide-1 (GLP-1) is an incretin derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a gut hormone. Its physiological functions include promoting insulin sensitivity, decreasing food intake by increasing satiety in brain and increasing insulin secretion from the pancreas in a glucose-dependent manner.
CAT# | 10-101-85 |
CAS | 107444-51-9 (net) |
Synonyms/Alias | Glucagon-Like Peptide 1 (7-36) amide; GLP1; GLP-1; Proglucagon; Glucagon-Like-Peptide |
M.F/Formula | C149H226N40O45 |
M.W/Mr. | 3297.68 |
Sequence | H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2 acetate salt |
Application | GLP-1 (7-36) amide Acetate augments glucose-induced insulin secretion and simultaneously inhibits glucagon secretion and gastric emptying. |
Areas of Interest | Diabetes |
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