Glucagons and Glucagon-Like Peptides (GLP-1 / GLP-2)

GLP-1 (7-36) amide Acetate

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CAT#
10-101-85
Synonyms/Alias
Glucagon-Like Peptide 1 (7-36) amide; GLP1; GLP-1; Proglucagon; Glucagon-Like-Peptide
CAS No.
107444-51-9 (net)
Sequence
H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2 acetate salt
M.W/Mr.
3297.68
Molecular Formula
C149H226N40O45
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
GLP-1 (7-36) amide Acetate augments glucose-induced insulin secretion and simultaneously inhibits glucagon secretion and gastric emptying.
Description
Glucagon-like peptide-1 (GLP-1) is an incretin derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a gut hormone. Its physiological functions include promoting insulin sensitivity, decreasing food intake by increasing satiety in brain and increasing insulin secretion from the pancreas in a glucose-dependent manner.
Areas of Interest
Diabetes
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