Peptide pool is a group of immunostimulatory antigen clusters, which is a collection of a large number of small peptides of specific length and different sequences. It includes the permutation and combinationRead More…
What is Peptide Microarray?
Definition of peptide microarrays Peptide microarrays (also commonly called peptide chips or peptide epitope microarrays) are designed based on protein-protein interactions, and a known protein array is immobilized on a carrier toRead More…
What PDC products are under development?
Recently, Oncopeptides announced that the FDA has accelerated the approval of its research product Pepaxto (melphalan flufenamide, also known as melflufen) to be marketed in combination with dexamethasone for the treatment ofRead More…
The First Anti-Cancer Peptide Conjugated Drug Has Recently Been Approved
The molecular weight of peptide drugs is between small molecule drugs (<500 Da) and biological products (>5000 Da). The FDA defines peptides as polymers composed of less than 40 amino acids (500-5000 Da).Read More…
Peptide Coupling, Oligonucleotides, Gene Therapy, And Other Emerging Therapies Have Achieved Multiple Breakthroughs
With the development of life sciences research, more and more rare disease-related targets have become known to people, and therapies spawned by new strategies are no longer limited to conventional small molecules.Read More…
MHC-peptide tetramer and its application
Introduction Antigen-specific cytotoxic T lymphocytes (CTL) kill target cells by recognizing the antigen peptides bound to major histocompatibility antigen (MHC)-I molecules on the cell surface. It is one of the body’s important immuneRead More…
Exenatide may be expected to help prevent or treat Parkinson’s disease
Recently, in a study published in the international journal Brain, scientists from University College London and other institutions found that drugs for type 2 diabetes may reduce the risk of Parkinson’s disease. InRead More…
The world’s first achondroplasia drug Vosoritide is under review of premarket approval in the EU
BioMarin is a global biotechnology company dedicated to the development and commercialization of innovative therapies for patients with serious and life-threatening rare genetic diseases. Recently, the company announced that it plans toRead More…
Study proposes a new strategy to intervene glutathione metabolism in the treatment of glioma
Recently, Xu Guowang, a researcher of the Biomolecular High-resolution Separation Analysis and Metabolomics Research Group of the Dalian Institute of Chemical Physics, Chinese Academy of Sciences, and the National Cancer Institute (NCI)Read More…
Researchers design peptide therapy for COVID-19
The pandemic of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 continues to cause severe health and economic disruptions with far-reaching effects. However, so far, no anti-SARS-CoV-2 drugs or vaccines have been approved, whichRead More…