16Sep/22

Brief Introduction to Covalent Peptide Drug Development

September 16, 2022drug discovery, Frontiers in PeptidesCovalent, Peptide drugs, Small moleculeppt

The effect of drugs is achieved by interfering with the pathogenic process by binding between drug molecules and receptors. The binding between the drug and the receptor protein, in addition to theRead More…

29Jul/22

Overview of Anti-Tumor Peptide Drugs

July 29, 2022drug discovery, Frontiers in Peptidesanti-cancer, Peptide drugs, Tumorppt

Peptide-based drug design has attracted much interest with the rapid growth of bioinformatics knowledge related to peptides and proteins. In the past, peptide-based drugs were not widely used due to some limitationsRead More…

08Apr/22

FDA Approved Cyclic Peptide Drugs

April 8, 2022drug discovery, Frontiers in PeptidesCyclic Peptides, FDA, Peptide drugsppt

Peptide drugs have many advantages over other classes of drugs: they are well tolerated, have stereochemistry that is easy to insert, thus providing selective targets, and can be very effective in interactingRead More…

25Jan/22

List of Marketed Peptide Drugs

January 25, 2022drug discovery, Frontiers in Peptides, NewsMarketed, Peptide, Peptide drugsppt

What is Peptide Drugs? Peptide is a type of compound formed by connecting multiple amino acids through peptide bonds, usually composed of 10-100 amino acid molecules, and its connection method is theRead More…

19May/21

What PDC products are under development?

May 19, 2021drug discoveryanti-cancer, PDC, peptide drug conjugateppt

Recently, Oncopeptides announced that the FDA has accelerated the approval of its research product Pepaxto (melphalan flufenamide, also known as melflufen) to be marketed in combination with dexamethasone for the treatment ofRead More…

09Apr/21

The First Anti-Cancer Peptide Conjugated Drug Has Recently Been Approved

April 9, 2021drug discovery, Frontiers in PeptidesAnti-Cancer Peptide, PDC, Peptide, peptide-drug conjugatesppt

The molecular weight of peptide drugs is between small molecule drugs (<500 Da) and biological products (>5000 Da). The FDA defines peptides as polymers composed of less than 40 amino acids (500-5000 Da).Read More…

04Nov/20

Exenatide may be expected to help prevent or treat Parkinson’s disease

November 4, 2020drug discoverydiabetes, exenatideppt

Recently, in a study published in the international journal Brain, scientists from University College London and other institutions found that drugs for type 2 diabetes may reduce the risk of Parkinson’s disease. InRead More…

31Aug/20

The world’s first achondroplasia drug Vosoritide is under review of premarket approval in the EU

August 31, 2020drug discoveryAchondroplasia, CNPppt

BioMarin is a global biotechnology company dedicated to the development and commercialization of innovative therapies for patients with serious and life-threatening rare genetic diseases. Recently, the company announced that it plans toRead More…

06May/20

Researchers design peptide therapy for COVID-19

May 6, 2020drug discoveryCOVIDppt

The pandemic of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 continues to cause severe health and economic disruptions with far-reaching effects. However, so far, no anti-SARS-CoV-2 drugs or vaccines have been approved, whichRead More…

14Jan/20

A portion of γδT cells bind under MHC-like molecules to identify harmful cells

January 14, 2020drug discovery, Newsanti-cancer, MHCppt

Cells are a key part of our immune system and play a key role in protecting us from harmful pathogens such as viruses and bacteria, as well as cancer. The more weRead More…