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Category: drug discovery

peptide drugs
drug discovery / News

FDA Approved Peptide Drugs in the First Half of 2023

The FDA’s Center for Drug Evaluation and Research (CDER) regulatory approval of a total of 26 NME (New Molecular Entity) drugs in the first half of 2023. It is worth …

Drug Discovery
drug discovery / Frontiers in Peptides

Classification of Impurities in Synthetic Peptide Drugs

Advantages of Peptides Peptides are a class of compounds formed by linking multiple amino acids through amide bonds, and their molecular size is between small molecule chemical drugs and macromolecular biological …

Analysis Methods for Peptide-Related Impurities
drug discovery / Experimental Techniques

Analysis Methods for Peptide-Related Impurities in Peptide Drugs

Background Peptide drugs, as a type of pharmaceutical with molecular weight between small molecule chemical drugs and biopolymers, provide more options for medicinal chemists and have become a hot research …

virus
drug discovery / Frontiers in Peptides

An Overview of Peptidomimetics-the Antiviral Drugs

Antiviral drugs Antiviral drugs are a class of drugs used to treat viral infections. While most antiviral drugs target specific viruses, broad-spectrum antivirals are effective against multiple viruses. Most of …

peptide drug
drug discovery / Frontiers in Peptides

Peptides for Gastrointestinal Studies

The gastrointestinal tract is the largest immune organ in the human body. The gastrointestinal tract refers to the digestive tract from the gastric pylorus to the anus, including the stomach, …

drug
drug discovery / Frontiers in Peptides

Drug Development of Intranasally Delivered Peptides

Intranasal (IN, intranasal) delivery of peptides has received considerable attention as a potential non-invasive delivery route through which peptide drugs can easily enter systemic circulation. Nasal delivery offers several advantages, …

Methods to improve the metabolic stability of peptides
drug discovery / Experimental Techniques

Methods to improve the metabolic stability of peptides

Given the rapid metabolism and short action time of peptide drugs, pharmaceutical chemists have explored a variety of methods to improve the metabolic stability of the peptide. The main recognition …

drug discovery / Frontiers in Peptides

Introduction to Peptide-based Checkpoint Inhibitors for Anti-Tumor

Background Recently, FDA approved the dual immunotherapy treatment for hepatocellular carcinoma with Astrazeneca’s Imjudo (tremelimumab) combined with Imfinzi (durvalumab), marking the second time of this year for the authoritative approval …

drug discovery / Frontiers in Peptides

Brief Introduction to Covalent Peptide Drug Development

The effect of drugs is achieved by interfering with the pathogenic process by binding between drug molecules and receptors. The binding between the drug and the receptor protein, in addition …

drug discovery / Frontiers in Peptides

Overview of Anti-Tumor Peptide Drugs

Peptide-based drug design has attracted much interest with the rapid growth of bioinformatics knowledge related to peptides and proteins. In the past, peptide-based drugs were not widely used due to …

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  • FDA Approved Peptide Drugs in the First Half of 2023
  • Classification of Impurities in Synthetic Peptide Drugs
  • Analysis Methods for Peptide-Related Impurities in Peptide Drugs
  • Plant Protein-Derived Antioxidant Peptides: An Overview
  • An Overview of Peptidomimetics-the Antiviral Drugs

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