19May/21

What PDC products are under development?

May 19, 2021drug discoveryanti-cancer, PDC, peptide drug conjugateppt

Recently, Oncopeptides announced that the FDA has accelerated the approval of its research product Pepaxto (melphalan flufenamide, also known as melflufen) to be marketed in combination with dexamethasone for the treatment ofRead More…

09Apr/21

The First Anti-Cancer Peptide Conjugated Drug Has Recently Been Approved

April 9, 2021drug discovery, Frontiers in PeptidesAnti-Cancer Peptide, PDC, Peptide, peptide-drug conjugatesppt

The molecular weight of peptide drugs is between small molecule drugs (<500 Da) and biological products (>5000 Da). The FDA defines peptides as polymers composed of less than 40 amino acids (500-5000 Da).Read More…

04Nov/20

Exenatide may be expected to help prevent or treat Parkinson’s disease

November 4, 2020drug discoverydiabetes, exenatideppt

Recently, in a study published in the international journal Brain, scientists from University College London and other institutions found that drugs for type 2 diabetes may reduce the risk of Parkinson’s disease. InRead More…

31Aug/20

The world’s first achondroplasia drug Vosoritide is under review of premarket approval in the EU

August 31, 2020drug discoveryAchondroplasia, CNPppt

BioMarin is a global biotechnology company dedicated to the development and commercialization of innovative therapies for patients with serious and life-threatening rare genetic diseases. Recently, the company announced that it plans toRead More…

06May/20

Researchers design peptide therapy for COVID-19

May 6, 2020drug discoveryCOVIDppt

The pandemic of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 continues to cause severe health and economic disruptions with far-reaching effects. However, so far, no anti-SARS-CoV-2 drugs or vaccines have been approved, whichRead More…

14Jan/20

A portion of γδT cells bind under MHC-like molecules to identify harmful cells

January 14, 2020drug discovery, Newsanti-cancer, MHCppt

Cells are a key part of our immune system and play a key role in protecting us from harmful pathogens such as viruses and bacteria, as well as cancer. The more weRead More…

12Dec/19

PNAS: study reveals how MHC dynamically binds antigen peptides

December 12, 2019drug discoveryMHC, peptidesppt

As one of the two primary classes of major histocompatibility complex (MHC) molecules, MHC class I molecules are expressed in almost all cell types and can present peptide antigens to CD8+ TRead More…

13Oct/19

GLP-1 drugs are expected to replace insulin to be the best choice for first-line treatment

October 13, 2019drug discoveryDiabetes Mellitus, Glucagons and Glucagon-Like Peptides (GLP-1 / GLP-2)ppt

  Diabetes mellitus (DM) is a group of metabolic diseases classified by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Diabetes is prevalent worldwide and the number of patientsRead More…

30Aug/19

How do new peptide molecules improve human health?

August 30, 2019drug discovery, NewsAlzheimer’s disease, Cell Penetrating Peptides, Creative Peptides, diabetesppt

Scientists are expected to develop a new type of cellular permeable peptide chimera to promote wound healing. In recent years, cell penetrating peptides as drug delivery carriers have aroused great interest amongRead More…

28Jun/19

The latest research report of Semaglutide

June 28, 2019drug discoveryGlucagons and Glucagon-Like Peptides (GLP-1 / GLP-2), Semaglutideppt

Novo Nordisk recently presented the latest data from two phase 3a clinical trials of its oral Semaglutide at the annual (ADA) meeting of the American Diabetes Association. Compared with the control drug,Read More…