Peptides for Gastrointestinal Studies
The gastrointestinal tract is the largest immune organ in the human body. The gastrointestinal tract refers to the digestive tract from the gastric pylorus to the anus, including the stomach, …
The gastrointestinal tract is the largest immune organ in the human body. The gastrointestinal tract refers to the digestive tract from the gastric pylorus to the anus, including the stomach, …
Intranasal (IN, intranasal) delivery of peptides has received considerable attention as a potential non-invasive delivery route through which peptide drugs can easily enter systemic circulation. Nasal delivery offers several advantages, …
Given the rapid metabolism and short action time of peptide drugs, pharmaceutical chemists have explored a variety of methods to improve the metabolic stability of the peptide. The main recognition …
Background Recently, FDA approved the dual immunotherapy treatment for hepatocellular carcinoma with Astrazeneca’s Imjudo (tremelimumab) combined with Imfinzi (durvalumab), marking the second time of this year for the authoritative approval …
The effect of drugs is achieved by interfering with the pathogenic process by binding between drug molecules and receptors. The binding between the drug and the receptor protein, in addition …
Peptide-based drug design has attracted much interest with the rapid growth of bioinformatics knowledge related to peptides and proteins. In the past, peptide-based drugs were not widely used due to …
Peptide drugs have many advantages over other classes of drugs: they are well tolerated, have stereochemistry that is easy to insert, thus providing selective targets, and can be very effective …
What is Peptide Drugs? Peptide is a type of compound formed by connecting multiple amino acids through peptide bonds, usually composed of 10-100 amino acid molecules, and its connection method …
Recently, Oncopeptides announced that the FDA has accelerated the approval of its research product Pepaxto (melphalan flufenamide, also known as melflufen) to be marketed in combination with dexamethasone for the …
The molecular weight of peptide drugs is between small molecule drugs (<500 Da) and biological products (>5000 Da). The FDA defines peptides as polymers composed of less than 40 amino acids …