Peptide synthesis, particularly solid-phase peptide synthesis (SPPS), is a widely employed method for creating peptides of varying lengths and sequences. The process has revolutionized the ability to produce synthetic peptides …
Background Peptide drugs, as a type of pharmaceutical with molecular weight between small molecule chemical drugs and biopolymers, provide more options for medicinal chemists and have become a hot research …
Given the rapid metabolism and short action time of peptide drugs, pharmaceutical chemists have explored a variety of methods to improve the metabolic stability of the peptide. The main recognition …
Classes of Cell-Penetrating Peptides There are many types of cell-penetrating peptides (CPPs), and their classification is based on physicochemical properties, sources, intake mechanisms, and biomedical applications. There is no unified …
In addition to the traditional chemotherapy, the main methods of treating tumors are usually platinum drugs, alkylating agents, paclitaxel and other cytotoxic molecules. Although these chemotherapeutics can effectively prevent or …
What is a peptide library Peptide library is a group of a large number of several million or more peptides arranged in sequence, that is, the combination of amino acid …
Introduction Alanine scanning library is one of the peptide library design tools. Alanine Scanning Library, this tool allows you to systematically substitute alanine for each amino acid position in your …
Definition of peptide microarrays Peptide microarrays (also commonly called peptide chips or peptide epitope microarrays) are designed based on protein-protein interactions, and a known protein array is immobilized on a …
Protein and peptide analysis employs many different tools to identify and characterize the immense variety of proteins that are expressed in a cell of any organism. Traditionally, sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) …
The peptide deformylase (PDF) is a unique feature of prokaryotes and believed not to exist in eukaryotes up to even only a few years ago. PDF is essential for ribosomal …