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Tag: MHC

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MHC-peptide tetramer and its application

Introduction Antigen-specific cytotoxic T lymphocytes (CTL) kill target cells by recognizing the antigen peptides bound to major histocompatibility antigen (MHC)-I molecules on the cell surface. It is one of the body’s …

drug discovery / News

A portion of γδT cells bind under MHC-like molecules to identify harmful cells

Cells are a key part of our immune system and play a key role in protecting us from harmful pathogens such as viruses and bacteria, as well as cancer. The …

drug discovery

PNAS: study reveals how MHC dynamically binds antigen peptides

As one of the two primary classes of major histocompatibility complex (MHC) molecules, MHC class I molecules are expressed in almost all cell types and can present peptide antigens to …

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PNAS: study reveals how MHC dynamically binds antigen peptides

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