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MHC-peptide tetramer and its application

Frontiers in Peptides

MHC-peptide tetramer and its application

Introduction Antigen-specific cytotoxic T lymphocytes (CTL) kill target cells by recognizing the antigen peptides bound to major histocompatibility antigen (MHC)-I molecules on the cell surface. It is one of the body’s …

drug discovery

Exenatide may be expected to help prevent or treat Parkinson’s disease

Recently, in a study published in the international journal Brain, scientists from University College London and other institutions found that drugs for type 2 diabetes may reduce the risk of Parkinson’s …

drug discovery

The world’s first achondroplasia drug Vosoritide is under review of premarket approval in the EU

BioMarin is a global biotechnology company dedicated to the development and commercialization of innovative therapies for patients with serious and life-threatening rare genetic diseases. Recently, the company announced that it …

News

Study proposes a new strategy to intervene glutathione metabolism in the treatment of glioma

Recently, Xu Guowang, a researcher of the Biomolecular High-resolution Separation Analysis and Metabolomics Research Group of the Dalian Institute of Chemical Physics, Chinese Academy of Sciences, and the National Cancer …

drug discovery

Researchers design peptide therapy for COVID-19

The pandemic of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 continues to cause severe health and economic disruptions with far-reaching effects. However, so far, no anti-SARS-CoV-2 drugs or vaccines have been …

News

Intravenous Aviptadil for COVID-19 Associated Acute Respiratory Distress (COVID-AIV)

Novel coronavirus (COVID-19) is known to cause acute respiratory distress syndrome (ARDS), which causes about 50 percent of ARDS deaths despite intensive care and mechanical ventilation. Therefore, patients with coronavirus …

News

FDA approves new indication for semaglutide to reduce cardiovascular risk in diabetic patients

Novo Nordisk announced that the FDA has approved a new indication of 0.5 mg or 1 mg of Ozempic (semaglutide) for reducing the risk of major adverse cardiovascular events (MACE), …

Frontiers in Peptides

Whether peptide is effective against coronavirus?

The 2019 Novel coronavirus is abbreviated by the World Health Organization. It is a positive-stranded single-stranded RNA coronavirus with an envelope, which is the pathogen of the pneumonia epidemic caused …

drug discovery / News

A portion of γδT cells bind under MHC-like molecules to identify harmful cells

Cells are a key part of our immune system and play a key role in protecting us from harmful pathogens such as viruses and bacteria, as well as cancer. The …

Frontiers in Peptides

Endocrinology: GnRH3 neuropeptide regulates PGC proliferation and sex differentiation in zebrafish

Gonadotropin-releasing hormone (GnRH), also known as luteinizing hormone-releasing hormone (LHRH), is a neurohormone secreted by the hypothalamus, which plays an important role in regulating the reproduction of vertebrates. Since the …

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Alzheimer’s disease and β-amyloid protein

Fundamentals of Modern Peptide Synthesis

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