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The world’s first achondroplasia drug Vosoritide is under review of premarket approval in the EU

drug discovery

The world’s first achondroplasia drug Vosoritide is under review of premarket approval in the EU

BioMarin is a global biotechnology company dedicated to the development and commercialization of innovative therapies for patients with serious and life-threatening rare genetic diseases. Recently, the company announced that it …

News

Study proposes a new strategy to intervene glutathione metabolism in the treatment of glioma

Recently, Xu Guowang, a researcher of the Biomolecular High-resolution Separation Analysis and Metabolomics Research Group of the Dalian Institute of Chemical Physics, Chinese Academy of Sciences, and the National Cancer …

drug discovery

Researchers design peptide therapy for COVID-19

The pandemic of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 continues to cause severe health and economic disruptions with far-reaching effects. However, so far, no anti-SARS-CoV-2 drugs or vaccines have been …

News

Intravenous Aviptadil for COVID-19 Associated Acute Respiratory Distress (COVID-AIV)

Novel coronavirus (COVID-19) is known to cause acute respiratory distress syndrome (ARDS), which causes about 50 percent of ARDS deaths despite intensive care and mechanical ventilation. Therefore, patients with coronavirus …

News

FDA approves new indication for semaglutide to reduce cardiovascular risk in diabetic patients

Novo Nordisk announced that the FDA has approved a new indication of 0.5 mg or 1 mg of Ozempic (semaglutide) for reducing the risk of major adverse cardiovascular events (MACE), …

Frontiers in Peptides

Whether peptide is effective against coronavirus?

The 2019 Novel coronavirus is abbreviated by the World Health Organization. It is a positive-stranded single-stranded RNA coronavirus with an envelope, which is the pathogen of the pneumonia epidemic caused …

drug discovery / News

A portion of γδT cells bind under MHC-like molecules to identify harmful cells

Cells are a key part of our immune system and play a key role in protecting us from harmful pathogens such as viruses and bacteria, as well as cancer. The …

Frontiers in Peptides

Endocrinology: GnRH3 neuropeptide regulates PGC proliferation and sex differentiation in zebrafish

Gonadotropin-releasing hormone (GnRH), also known as luteinizing hormone-releasing hormone (LHRH), is a neurohormone secreted by the hypothalamus, which plays an important role in regulating the reproduction of vertebrates. Since the …

drug discovery

PNAS: study reveals how MHC dynamically binds antigen peptides

As one of the two primary classes of major histocompatibility complex (MHC) molecules, MHC class I molecules are expressed in almost all cell types and can present peptide antigens to …

drug discovery

GLP-1 drugs are expected to replace insulin to be the best choice for first-line treatment

  Diabetes mellitus (DM) is a group of metabolic diseases classified by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Diabetes is prevalent worldwide and the number …

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