Peptides for Gastrointestinal Studies
The gastrointestinal tract is the largest immune organ in the human body. The gastrointestinal tract refers to the digestive tract from the gastric pylorus to the anus, including the stomach, …
Drug Development of Intranasally Delivered Peptides
Intranasal (IN, intranasal) delivery of peptides has received considerable attention as a potential non-invasive delivery route through which peptide drugs can easily enter systemic circulation. Nasal delivery offers several advantages, …
Methods to improve the metabolic stability of peptides
Given the rapid metabolism and short action time of peptide drugs, pharmaceutical chemists have explored a variety of methods to improve the metabolic stability of the peptide. The main recognition …
Introduction to Peptide-based Checkpoint Inhibitors for Anti-Tumor
Background Recently, FDA approved the dual immunotherapy treatment for hepatocellular carcinoma with Astrazeneca’s Imjudo (tremelimumab) combined with Imfinzi (durvalumab), marking the second time of this year for the authoritative approval …
Brief Introduction to Covalent Peptide Drug Development
The effect of drugs is achieved by interfering with the pathogenic process by binding between drug molecules and receptors. The binding between the drug and the receptor protein, in addition …
Overview of Anti-Tumor Peptide Drugs
Peptide-based drug design has attracted much interest with the rapid growth of bioinformatics knowledge related to peptides and proteins. In the past, peptide-based drugs were not widely used due to …
Classes and Applications of Cell-Penetrating Peptides
Classes of Cell-Penetrating Peptides There are many types of cell-penetrating peptides (CPPs), and their classification is based on physicochemical properties, sources, intake mechanisms, and biomedical applications. There is no unified …
FDA-Approved Cyclic Peptide Drugs
Peptide drugs have many advantages over other classes of drugs: they are well tolerated, have stereochemistry that is easy to insert, thus providing selective targets, and can be very effective …
What is Animal Peptides, Plant Peptides and Synthetic Peptides?
Peptide has become a favorite in the food field. Its application in the field of functional food, special-purpose food, and health food is becoming more and more popular. Various peptides …
Classification of Antimicrobial Peptides
Antimicrobial peptides (AMPs) are a class of small peptides that widely exist in nature and they are an important part of the innate immune system of different organisms. So far, …