FDA approved ALM201 for ovarian cancer
Ovarian cancer is caused by one kind of malignant tumor of ovarian neoplasms, which refers to malignant tumor cells surviving on women’s ovaries. 90%~95% of those tumor cells induce primary …
Broccoli Reduces Blood Sugar levels for diabetic people
Broccoli is a good food source of chromium, as one cup cooked broccoli contains 22 micrograms of chromium, 10 times that other food contains. Chromium plays an important role in …
Bacterial peptide deformylase inhibitor PMT analogs inhibit cancer cell growth by interacting with human peptide deformylase
The peptide deformylase (PDF) is a unique feature of prokaryotes and believed not to exist in eukaryotes up to even only a few years ago. PDF is essential for ribosomal …
The incretin hormones: GLP-1 and GIP
Glucagon-like peptide-1(GLP-1) and glucose-depended insulinotropic polypeptide (GIP) are the two peptides that have been confirmed to act as incretin hormones to date. GIP was the first incretin hormone identified. It …
Diagnosis and Management of Female Sexual Arousal Disorder
Although female sexual arousal disorder (FSAD) is prevalent, it is often not well defined or understood. The current definition of FSAD discussed below is based on the Diagnostic and Statistical Manual of Mental Disorders, …
Use of Teduglutide to Reduce Parenteral Support in Short Bowel Syndrome
Home parenteral nutrition (HPN) has saved the lives of thousands of short bowel syndrome (SBS) patients with intestinal failure (IF) since the introduction in the late 1960s. SBS-IF patients have inadequate absorption …
Cell Penetrating Peptides
During the last decade, Cell-Penetrating Peptides (CPPs) have been investigated for their ability to overcome the cell membrane barrier for the intracellular or transcellular delivery of cargoes, such as many low molecular …
Implications for the use and study of amyloid in therapeutics, bionanomaterials, and biophysics
Therapeutics The structure of amyloid fibrils has been sought for a number of proteins involved in amyloid diseases. One of the main goals for determining the structure of amyloid has been …
Liraglutide-Glucagon-like peptide 1 analogues
Islet transplantation is an emerging therapeutic option for the treatment of select labile type 1 diabetes mellitus patients. The announcement of the first consecutive series of successful islet transplants in type 1 diabetic …
Misunderstanding of Peptide Synthesis
Since 1963, Merrifield has successfully developed solid phase peptide synthesis (SPPS) method, and through continuous improvement & perfection, nowadays this method has become a common technology used in modern peptide …