Alzheimer’s disease and β-amyloid protein
Alzheimer’s disease (AD) is the most common cause of dementia and is considered the biggest public health hazard of our generation, affecting more than 20 million people. About 135 million …
Cell-Penetrating Peptides
Cell-penetrating peptides (CPPs), alternatively designated as protein transduction domains (PTDs), Trojan peptides, model amphipathic peptides (MAPs), or membrane translocating sequences (MTSs), have the ability to translocate the cell membrane and …
California research team develops universal cancer peptide vaccine
The research team at the Dr. Rath Research Institute in California Institute of Natural Health Education has developed a cancer vaccine that effectively inhibits tumor growth. This peptide vaccine is …
2018 Nobel Prize in Medicine Cancer therapy: Negative immune regulation
The Nobel Prize in Physiology or Medicine 2018 was awarded to James P, Allison and Tasuku Honjo “for their discovery of cancer therapy by inhibition of negative immune regulation.” The Nobel …
Alzheimer’s disease and diabetes: hope for inhibitors against amyloid plaques
Amyloid self-assembly is linked to the pathogenesis of Alzheimer’s disease (AD) and type Ⅱ diabetes (T2D), Several teams of scientists around the world are working on finding ways to prevent amyloid plaque …
Agonists and antagonists for NPY-family receptors
Peptide ligands Over the past four years there’s been considerable progress in the development of novel selective analogs of NPY. A number of these analogs have been directed toward discovering tools to …
NPY in allergic and respiratory disorders
Introduction The respiratory tract can be divided into upper airway including the nasal cavities, the pharynx and larynx, and the lower airway comprising the tracheobronchial tract and the respiratory portion …
What is Interferon?
The cytokine family Cytokines are an important group of proteins realizing intercellular communications among cells of the same tissue (paracrine) or of different tissues (endocrine). Such communications are essential for the correct synchronized reactions …
The application of Peptide nucleic acids (PNAs)
The definition of Peptide nucleic acids (PNAs) PNAs are synthetic DNA analogs in which the phosphodiester backbone is replaced by repetitive units of N-(2-aminoethyl) glycine to which the purine and pyrimidine bases …
Novel neuropeptide may hold clues to the risk of obesity and diabetes
Obesity is a chronic, multidimensional problem which is being increasingly seen in younger patients. Besides obesity is becoming an epidemic in industrialized countries and is continuing to increase in developing …