12Dec/19

PNAS: study reveals how MHC dynamically binds antigen peptides

December 12, 2019drug discoveryMHC, peptidesppt

As one of the two primary classes of major histocompatibility complex (MHC) molecules, MHC class I molecules are expressed in almost all cell types and can present peptide antigens to CD8+ TRead More…

13Oct/19

GLP-1 drugs are expected to replace insulin as the best choice for first-line treatment of type 2 diabetes mellitus.

October 13, 2019drug discoveryDiabetes Mellitus, Glucagons and Glucagon-Like Peptides (GLP-1 / GLP-2)ppt

Diabetes is a group of metabolic diseases classified by chronic hyperglycemia resulting from defects in insulin secretion, insulin action or both. The prevalence of diabetes mellitus (DM) worldwide is drastically rising, withRead More…

30Aug/19

How do new peptide molecules improve human health?

August 30, 2019drug discovery, NewsAlzheimer’s disease, Cell Penetrating Peptides, Creative Peptides, diabetesppt

Scientists are expected to develop a new type of cellular permeable peptide chimera to promote wound healing. In recent years, cell penetrating peptides as drug delivery carriers have aroused great interest amongRead More…

28Jun/19

The latest research report of Semaglutide

June 28, 2019drug discoveryGlucagons and Glucagon-Like Peptides (GLP-1 / GLP-2), Semaglutideppt

Novo Nordisk recently presented the latest data from two phase 3a clinical trials of its oral Semaglutide at the annual (ADA) meeting of the American Diabetes Association. Compared with the control drug,Read More…

30May/19

Peptide drugs from poisons

May 30, 2019drug discovery, Frontiers in PeptidesPeptide drugs, poisonppt

Some of the deadliest animals on earth are toxic. Poison is their deadly weapon to defend themselves or attack. Toxins are injected into the skin and become poison. There are hundreds ofRead More…

29Apr/19

Sulforaphane, an anticancer substance.

April 29, 2019drug discovery, Newsanti-cancer, Sulforaphaneppt

Sulforaphane, chemical name is 1-isothiocyanate-4-methanesulfonyl butane, also known as “sulforaphane”, which is a common antioxidant and rich in broccoli, cabbage, broccoli, kale, carrots, and other cruciferous plants. Some research showed it isRead More…

15Apr/19

Scientists identify potential target protein aggregates for Alzheimer’s disease.

April 15, 2019drug discovery, NewsAlzheimer’s diseaseppt

Recently, a study published in the international journal Stem Cell Reports, Scientists from institutions such as the University of Paris IV have identified potential targets for the treatment of Alzheimer’s disease. TheRead More…

14Feb/19

Progress of several anti-aging therapies

February 14, 2019drug discoveryaging, cosmeticsppt

For thousands of years, a human has never stopped chasing the dream of “immortality”. With the development of biology, we have a new understanding of the word “immortality” and recognize the boundaries ofRead More…

29Jan/19

Alzheimer’s disease and β-amyloid protein

January 29, 2019drug discoveryAlzheimer’s disease, Aβppt

Alzheimer’s disease (AD) is the most common cause of dementia and is considered the biggest public health hazard of our generation, affecting more than 20 million people. About 135 million people willRead More…

28Sep/18

Alzheimer’s disease and diabetes: hope for inhibitors against amyloid plaques

September 28, 2018drug discoveryppt

Amyloid self-assembly is linked to the pathogenesis of Alzheimer’s disease (AD) and type Ⅱ diabetes (T2D), Several teams of scientists around the world are working on finding ways to prevent amyloid plaque formation inRead More…