Protease-Activated Receptor-2 Activating Peptide

Protease-Activated Receptor-2 Activating Peptide is an agonist of Protease-Activated Receptor-2 (PAR-2).

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CAT#R1636
Chemical Structure
CAS171436-38-7
Synonyms/AliasThrombin Receptor-Like 1 (1-6) amide (mouse, rat), SLIGRLamide, Proteinase Activated Receptor 2 (1-6) amide (mouse, rat), Coagulation Factor II Receptor-Like 1 (1-6) amide (mouse, rat)
M.F/FormulaC₂₉H₅₆N₁₀O₇
M.W/Mr.656.82
SequenceOne Letter Code: SLIGRL-NH2
three Letter Code: Ser-Leu-Ile-Gly-Arg-Leu-NH2
Biological ActivityAgonist peptide derived from the N-terminus of protease-activated receptor-2 (PAR2). Activates PAR2 (EC50 ~ 5 μM) and facilitates gastrointestinal transit in mice in vivo.
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