Peptide Profiling

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Peptide profiling needs to comprehensively consider the protein itself, the purpose of the experiment and the expected results, and requires high-quality sample pretreatment technology, strong technical separation ability and information in order to obtain the best separation of protein hydrolyzed digestibles and carry out reliable characterization and analysis of peptides. As a specialist in biomedical related technical services, Creative Peptides is able to provide peptide profiling services for customers in a efficient and cost-effective way of best quality.

Introduction

Peptide profiling is based on the molecular weight and amino acid composition of proteins and peptides, and uses specific proteolytic enzymes (usually endopeptidase) to act on special peptide chain sites to cleave peptides into small fragments, and then form characteristic fingerprints by certain means of separation and detection. Peptide profiling is of great significance for the study of the structure and characterization of peptides.

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References

  1. Villanueva, J., Lawlor, K., Toledo-Crow, R., & Tempst, P. (2006). Automated serum peptide profiling. Nature protocols, 1(2), 880-891.
  2. Okerberg, E. S., Wu, J., Zhang, B., Samii, B., Blackford, K., Winn, D. T., ... & Patricelli, M. P. (2005). High-resolution functional proteomics by active-site peptide profiling. Proceedings of the National Academy of Sciences, 102(14), 4996-5001.
  3. Solieri, L., Baldaccini, A., Martini, S., Bianchi, A., Pizzamiglio, V., & Tagliazucchi, D. (2020). Peptide profiling and biological activities of 12-month ripened Parmigiano Reggiano cheese. Biology, 9(7), 170.
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Creative Peptides is a custom lab chemical supplier that provides a wide range of peptides for the pharmaceutical and biotechnology industries.

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