Targeting Peptide Design and Screening
Strong Target Affinity & SelectivityCustomized for Your Delivery System
With the continuous pursuit of precision therapy in the biopharmaceutical field, targeting peptides-molecular tools that combine high specificity with excellent biocompatibility-are becoming important players in drug development, diagnostic reagents, and targeted delivery systems. We are committed to providing our clients with one-stop Targeting Peptide services, covering everything from target analysis and peptide sequence design to efficient screening and validation, helping you rapidly discover high-affinity and highly specific targeting peptides to drive breakthroughs in new drug development and precision medicine.
Leveraging advanced bioinformatics technologies, diverse peptide library construction platforms, and extensive screening experience, we offer customized and optimized Targeting Peptide solutions that cover all stages from basic research to preclinical development. Whether targeting cell surface receptors, enzymes, or pathology-related proteins, we provide professional and efficient Targeting Peptide design and screening services to support your research and industrialization process.
Our Targeting Peptide Design and Screening Services
01Targeting Peptide Sequence Design
Design Targeting Peptide sequences based on the structure and function of target proteins, combined with bioinformatics tools
Use molecular docking simulations to predict peptide-target binding sites and affinities
Structural optimization to enhance peptide stability and specificity
02Peptide Library Construction
Synthesize diverse random peptide libraries (linear peptide libraries, cyclic peptide libraries, constrained cyclic peptide libraries, etc.)
Design directed peptide libraries for specific targets
Synthesize peptide display vectors (such as phage display, bacterial display, peptide expression vectors)
03High-Throughput Screening Technologies
Phage display technology to screen high-affinity targeting peptides
Yeast display technology for screening and characterization
Synthetic peptide microarray screening and binding analysis
Biophysical methods such as SPR (Surface Plasmon Resonance) and BLI (Biolayer Interferometry) to assist screening
04Peptide-Target Binding Affinity Measurement
Use SPR, BLI, ITC (Isothermal Titration Calorimetry), and other techniques to measure peptide-target binding constants
Cell surface binding analysis (flow cytometry, immunofluorescence, etc.)
05Peptide Activity and Specificity Validation
In vitro cellular functional assays (cell uptake, competitive binding, signaling pathway activation/inhibition, etc.)
Intracellular localization studies
Targeting ability validation in animal models (immunohistochemistry, in vivo imaging, etc.)
06Peptide Stability and Pharmacokinetics Optimization
Evaluate peptide enzymatic stability
Modification designs (cyclization, D-amino acid substitution, PEGylation, etc.) to improve stability and in vivo half-life
Metabolic pathway and biodistribution studies
07Custom Synthesis and Modification of Targeting Peptides
Custom synthesis of Targeting Peptides to meet research and development needs
Various labeling methods including fluorescent, biotin, and radioactive labels
Design and synthesis of peptide linkers suitable for conjugation with drugs or nanocarriers
08Data Analysis and Reporting
Provide Targeting Peptide screening and analysis reports combining bioinformatics and experimental data
Recommend peptide optimization strategies and directions for further development
Why Choose Us? - Key Advantages of Our Targeting Peptide Design and Screening Services
01One-Stop Customized Solutions
Provide a complete service chain from target analysis, peptide design to screening and validation, saving clients time and cost.
02Diverse Peptide Library Platforms
Support various library construction methods including linear peptides, cyclic peptides, and peptide display, covering different target requirements.
03Advanced Screening Technologies
ombine phage display, high-throughput microarrays, and biophysical detection techniques to ensure accurate and reliable screening results.
04Experienced R&D Team
With years of practical experience in Targeting Peptide design and screening, flexibly tailor solutions based on client needs.
05Personalized Peptide Modification Services
Offer a variety of chemical and biological labeling modifications to meet the needs of drug delivery, imaging, diagnostics, and other applications.
06Efficient Communication and Rapid Delivery
Emphasize client communication to ensure transparent and timely project progress and quick delivery of high-quality results.
Step-by-Step Targeting Peptide Design and Screening Service Procedure
1Requirement Communication and Target Confirmation
Deeply understand the client's research goals and target information to clarify peptide screening requirements.
2Targeting Peptide Design and Peptide Library Construction
Design Targeting Peptide sequences based on the target's structure and function, and synthesize diverse peptide libraries (linear peptide libraries, cyclic peptide libraries, etc.).
3High-Throughput Screening and Enrichment
Use technologies such as phage display, yeast display, or peptide microarrays for high-throughput screening and enrichment of high-affinity candidate peptides.
4Binding Affinity and Specificity Validation
Measure peptide-target binding affinity using techniques like SPR and BLI, and validate targeting specificity via cell-based assays.
5Peptide Optimization and Functional Evaluation
Optimize peptide structures based on validation results and evaluate their stability and functional performance.
6Custom Synthesis and Labeling Modifications
Synthesize optimized Targeting Peptides and provide various functional modification services to meet subsequent R&D needs.
7Data Analysis and Report Delivery
Provide detailed screening data and technical reports to assist clients in their subsequent development.
Application Areas of Targeting Peptides
Targeted Drug Development
Used to discover high-affinity targeting peptides as active pharmaceutical ingredients or drug carriers.
Tumor-Targeted Therapy
Design targeting peptides against tumor markers for precise therapy and targeted delivery.
Diagnostic Reagent Development
Applied in biomarker detection to assist early disease diagnosis.
Targeted Modification of Nanodrug Carriers
Modify nanoparticles to achieve targeted delivery and improve drug targeting and bioavailability.
Immune Modulation and Vaccine Design
Develop peptides targeting immune cells to aid immunotherapy and vaccine optimization.
Cell-Targeted Delivery
Used to deliver gene editing tools, nucleic acid drugs, etc., for cell-specific delivery.
FAQ
1. What are targeting peptides?
Targeting peptides are short peptide sequences that specifically recognize and bind particular targets (such as proteins or receptors). They are commonly used in drug development, diagnostics, and targeted delivery.
2. What targeting peptide screening technologies do you use?
We mainly use phage display, yeast display, high-throughput peptide microarrays, combined with affinity measurements (such as SPR, BLI), to ensure accurate and efficient screening results.
3. Do you support custom synthesis and modification of targeting peptides?
Yes, we provide various peptide modifications (fluorescent, PEGylation, biotinylation, etc.) and custom synthesis services to meet different application needs.
4. What information is needed for Targeting Peptide design?
Typically, the protein sequence and structural information (if available) of the target, as well as the specific project requirements and application direction, are needed.
5. How do you ensure the specificity and affinity of screened peptides?
We enrich peptides through multiple rounds of screening and verify their binding affinity and targeting specificity by various biophysical and cell-based assays to ensure quality.
6. Can the screened targeting peptides be directly used in in vivo experiments?
Generally, we recommend performing stability and functional optimization, as well as necessary in vitro and in vivo validations first. We also provide related optimization and evaluation services.
