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Creative Peptides relies on its proprietary peptide technology to establish an efficient, stable and high-throughput peptide synthesis platform to provide customers with various label peptides. Among them, peptide biotinylation is an effective method to specifically bind peptides to the surface of streptavidin coating.
Creative Peptides routinely synthesizes peptides with the biotin tags. The label is usually attached to the N-terminal or C-terminal, and the N-terminal biotinylation can be carried out directly on the primary amino group, while the biotinylation is usually carried out on the ε-amino group of C-terminal lysine. In the preparation of biotinylated peptides, an important consideration is to ensure that there are sufficient spacers between the biotin groups and the amino acids expected to interact with macromolecules in the peptides. To avoid spatial barriers, a junction can be inserted between biotin and peptide sequences. Peptides are separated from peptides by various so-called connectors or spacers with different lengths and polarities.
References
Creative Peptides has accumulated a huge library of peptide knowledge including frontier peptide articles, application of peptides, useful tools, and more!
Rotigaptide is a novel antiarrhythmic peptide that enhances gap junction (GJ) intercellular conductance between cardiomyocy ...
PR 39, a porcine 39-aa peptide antibiotic, was originally isolated from the upper part of the small intestine o ...
IGF-1 IGF-1 is a single chain peptide consists of 70 amino acids in four domains, B, C, A and D. The A- and B-domains are str ...
Studies on the binding affinities of darifenacin hydrobromide and human muscarinic receptor subtypes show strong ...
Long-term potentiation (LTP) is a persistent synaptic enhancement which is thought to be a substrate for memory. ...