Biotinylated Peptides

* Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

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Creative Peptides relies on its proprietary peptide technology to establish an efficient, stable and high-throughput peptide synthesis platform to provide customers with various label peptides. Among them, peptide biotinylation is an effective method to specifically bind peptides to the surface of streptavidin coating.

Application of Biotinylated Peptides

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Creative Peptides routinely synthesizes peptides with the biotin tags. The label is usually attached to the N-terminal or C-terminal, and the N-terminal biotinylation can be carried out directly on the primary amino group, while the biotinylation is usually carried out on the ε-amino group of C-terminal lysine. In the preparation of biotinylated peptides, an important consideration is to ensure that there are sufficient spacers between the biotin groups and the amino acids expected to interact with macromolecules in the peptides. To avoid spatial barriers, a junction can be inserted between biotin and peptide sequences. Peptides are separated from peptides by various so-called connectors or spacers with different lengths and polarities.

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References

  1. Zhang, M., Ai, W. W., Mei, Z. L., Hu, Y. H., & Zhang, Z. L. (2017). Delivery of biotinylated IGF-1 with biotinylated self-assembling peptides combined with bone marrow stem cell transplantation promotes cell therapy for myocardial infarction. Experimental and therapeutic medicine, 14(4), 3441-3446.
  2. Sato, A., & Ebina, K. (2019). A biotinylated peptide, BP21, alleviates hypotension in anaphylactic mice. Journal of Peptide Science, 25(8), e3197.
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.

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Creative Peptides is a custom lab chemical supplier that provides a wide range of peptides for the pharmaceutical and biotechnology industries.

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