* Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).
Creative Peptides is pleased to provide you with a continuously growing and diverse portfolio of PEGs which will help you improve the success of your drug discovery research. For Peptide PEGylation, we usually use standard amide bond formation to connect PEG to peptides, but we can also use other linking chemicals (for example, mercapto-Maleimide, oxime binding, click chemistry). Pegylated peptides can overcome many challenges of candidate peptide drugs.
Peptides play a key role in the pharmaceutical industry and drug treatment development, but their application in vivo is limited due to rapid protease degradation, poor solubility, poor antigen reaction and glomerular filtration of the kidney. The covalent binding of polyethylene glycol (PEG) chain to peptides is a way to reduce immunogenicity, improve solubility and reduce renal clearance. The addition of monodisperse PEG chain may be a factor in the development of safe and effective pegylated peptides and is essential for achieving the best therapeutic effect.
References
Creative Peptides is a custom lab chemical supplier that provides a wide range of peptides for the pharmaceutical and biotechnology industries.
Appropriate perfusion preservation solution is of great significance for reducing or slowing down various damage ...
As a small actin-binding protein upregulated in highly metastatic prostate cancer cells, thymosin β15 (Tβ15) has ...
of Tripeptide-1 The tripeptide-1 (glycyl-L-histadyl-L-lysine or GHK) is primarily known as carrier peptides. It ...
Peptide YY is referred to as PYY. Its structure is highly homologous with pancreatic polypeptide (PP) and neurop ...
The mammalian precursor gene proglucagon, which contains the glucagon sequence together with two structurally related glucago ...