Formulation Development

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Overview of drug formulation

Pharmaceutical products are formulated products with specific dosage forms for efficient delivery and product stability. Formulation development serves the purpose to determine the optimal dosage form, composition and manufacturing route for pharmaceutical products.

Formulation development

There are different kinds of pharmaceutical dosage forms such as:

  • Oral tablets
  • Capsules
  • Solutions
  • Suspensions
  • Topical ointments
  • Gels
  • Injections for intravenous (IV), intramuscular (IM), or subcutaneous (SC) administration.

They require different production technologies and at the same time present different challenges for the study. DOE (design of experiments) is used as a routine for formulation development, and it evaluates all potential factors simultaneously, systematically, and quickly.

Steps of formulation development

A formulation contains the active pharmaceutical ingredient (API) and other inactive excipients.

Creative Peptides offers design and optimization of formulations from early pre-clinical stage to Phase I and Phase II clinical trials and commercial manufacturing. We are dedicated to help you achieve the optimal formulation for your APIs.

References

  1. Chaurasia, G. (2016). A review on pharmaceutical preformulation studies in formulation and development of new drug molecules. International Journal of Pharmaceutical Sciences and Research, 7(6), 2313.
  2. Honmane, S. M. (2017). General Considerations of Design and Development of Dosage Forms: Pre-formulation Review. Asian Journal of Pharmaceutics (AJP): Free full text articles from Asian J Pharm, 11(03).
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Creative Peptides is a custom lab chemical supplier that provides a wide range of peptides for the pharmaceutical and biotechnology industries.

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