Customized Delivery Strategy DesignEnhanced Tissue and Cell Targeting
We offer comprehensive custom services for the development of peptide-based targeted delivery systems, supporting drug discovery, diagnostics, and therapeutic research. By combining advanced peptide engineering with a wide range of delivery vectors, we design and manufacture precision delivery platforms tailored to your specific application needs.
Custom design of high-affinity peptide ligands targeting specific receptors or tissues (e.g., tumor-homing peptides: RGD, NGR, LyP-1)
Sequence optimization and stability enhancement
PEGylation (linear or branched)
Lipid conjugation (e.g., palmitic acid, stearic acid)
Cyclization (head-to-tail, disulfide bridges)
Terminal capping (acetylation/amidation)
Customization of delivery carriers, including:
Liposomes
Lipid Nanoparticles (LNPs)
Polymeric Nanoparticles (e.g., PLGA, PEG-PCL, PEI)
Exosome-mimicking systems
Inorganic nanoparticles (e.g., gold, silica, quantum dots)
Peptide-to-carrier conjugation strategies:
Covalent linkage (e.g., click chemistry, amide bond)
Electrostatic interaction or hydrophobic adsorption
Surface decoration or ligand insertion
Co-delivery platform design:
Peptide + small molecule drug
Peptide + nucleic acid (siRNA, mRNA, ASO, CRISPR)
Peptide + protein or antibody
Stimuli-responsive delivery systems:
pH-sensitive, enzyme-cleavable, or redox-sensitive carriers
Cell-penetrating peptide (CPP) integration:
Custom synthesis of TAT, Penetratin, Transportan, and CPP-targeting hybrids
Particle size, zeta potential, and polydispersity (PDI)
Drug loading efficiency and release profile testing
Cellular uptake assay (upon request)
Targeting efficacy evaluation (e.g., FACS, confocal microscopy)
Stability analysis under biological and storage conditions
GMP or cGMP-compliant peptide synthesis and delivery system manufacturing for preclinical or clinical applications
Comprehensive quality documentation: COA, MS, HPLC, endotoxin, residual solvent analysis, etc.
Fully tailored development strategies: from target identification to in vivo validation
Flexible NDA/CDA collaboration models to protect client IP
Peptide Expertise
Over a decade of experience in custom peptide synthesis and ligand design
Integrated One-Stop Service
From design, synthesis, and carrier development to analytical validation
Broad Delivery Carrier Toolbox
Lipid, polymer, inorganic, and biologically derived nanocarriers
Flexible Conjugation Options
Covalent, electrostatic, hydrophobic, or click chemistry-based linking
Rapid Turnaround & Responsive Support
Fast project initiation and transparent project tracking
Customizable for Research or GMP Use
R&D-scale and GMP-grade options available for preclinical and clinical pipelines
Understand target type (e.g., tumor cells, receptors, tissues)
Define delivery goals: small molecule, RNA, protein, etc.
Choose appropriate delivery route and formulation needs
Custom peptide ligand design based on target
Structural modeling, sequence tuning, and modifications
Recommend optimal nanocarrier (LNP, polymer, exosome, etc.)
Peptide-to-carrier conjugation strategy and formulation design
Peptide synthesis with analytical QC
Nanocarrier formulation with or without payload encapsulation
Particle size, zeta potential, encapsulation efficiency
In vitro targeting and uptake evaluation (optional)
Scale-up under R&D or GMP conditions (upon request)
Provide analytical reports, formulation protocol, and QC results
Secure packaging under required storage conditions
Worldwide shipping with full documentation support
Empowering Drug Discovery, Gene Therapy, and Diagnostics
Tumor-homing peptides guiding drug-loaded nanoparticles to tumors
Targeted LNP or polymer carriers for siRNA, mRNA, or CRISPR payloads
BBB-penetrating peptides for brain-targeted systems
Dual-targeting strategies for immuno-oncology and autoimmune diseases
Peptide-guided contrast agents or fluorescent probes for molecular imaging
Targeted antimicrobial peptides or payloads directed at pathogens or infected cells
Ligand-guided delivery platforms for patient-specific molecular profiles
We offer a wide range of nanocarrier platforms including lipid nanoparticles (LNPs), liposomes, polymeric nanoparticles (e.g., PLGA, PEG-PCL), inorganic nanoparticles (gold, silica), and exosome-inspired vesicles. All can be functionalized with custom peptide ligands for targeted delivery.
Yes. We support both full-service projects and collaborative models. You can provide your own peptide, nanoparticle formulation, or both-we'll assist with conjugation, optimization, and characterization as needed.
We specialize in rational design and synthesis of custom peptides targeting tumor markers, cell surface receptors (e.g., integrins, transferrin receptor, EGFR), tissues (e.g., liver, brain), or disease-specific microenvironments (e.g., acidic pH, enzymes).
Absolutely. We can integrate CPPs like TAT, Penetratin, Transportan, or custom-designed CPPs into your delivery system to facilitate intracellular or nuclear delivery.
We provide optional in vitro testing services such as cellular uptake assays, FACS analysis, and confocal imaging. In vivo studies may be supported through CRO partners or client collaboration.
