Targeted Delivery System Customization Services

Customized Delivery Strategy DesignEnhanced Tissue and Cell Targeting

We offer comprehensive custom services for the development of peptide-based targeted delivery systems, supporting drug discovery, diagnostics, and therapeutic research. By combining advanced peptide engineering with a wide range of delivery vectors, we design and manufacture precision delivery platforms tailored to your specific application needs.

Our Targeted Delivery System Services

01

Targeting Peptide Design & Synthesis

Custom design of high-affinity peptide ligands targeting specific receptors or tissues (e.g., tumor-homing peptides: RGD, NGR, LyP-1)

Sequence optimization and stability enhancement

Peptide modification options:

PEGylation (linear or branched)

Lipid conjugation (e.g., palmitic acid, stearic acid)

Cyclization (head-to-tail, disulfide bridges)

Terminal capping (acetylation/amidation)

02

Nanocarrier Platform Development

Customization of delivery carriers, including:

Liposomes

Lipid Nanoparticles (LNPs)

Polymeric Nanoparticles (e.g., PLGA, PEG-PCL, PEI)

Exosome-mimicking systems

Inorganic nanoparticles (e.g., gold, silica, quantum dots)

Peptide-to-carrier conjugation strategies:

Covalent linkage (e.g., click chemistry, amide bond)

Electrostatic interaction or hydrophobic adsorption

Surface decoration or ligand insertion

03

Peptide-Enabled Drug Delivery Systems

Co-delivery platform design:

Peptide + small molecule drug

Peptide + nucleic acid (siRNA, mRNA, ASO, CRISPR)

Peptide + protein or antibody

Stimuli-responsive delivery systems:

pH-sensitive, enzyme-cleavable, or redox-sensitive carriers

Cell-penetrating peptide (CPP) integration:

Custom synthesis of TAT, Penetratin, Transportan, and CPP-targeting hybrids

04

Analytical Characterization Services

Particle size, zeta potential, and polydispersity (PDI)

Drug loading efficiency and release profile testing

Cellular uptake assay (upon request)

Targeting efficacy evaluation (e.g., FACS, confocal microscopy)

Stability analysis under biological and storage conditions

05

GMP or cGMP-compliant peptide synthesis and delivery system manufacturing for preclinical or clinical applications

Comprehensive quality documentation: COA, MS, HPLC, endotoxin, residual solvent analysis, etc.

06

Collaborative Custom Development

Fully tailored development strategies: from target identification to in vivo validation

Flexible NDA/CDA collaboration models to protect client IP

Why Partner with Us for Targeted Delivery Development?

01Peptide Expertise

Over a decade of experience in custom peptide synthesis and ligand design

02Integrated One-Stop Service

From design, synthesis, and carrier development to analytical validation

03Broad Delivery Carrier Toolbox

Lipid, polymer, inorganic, and biologically derived nanocarriers

04Flexible Conjugation Options

Covalent, electrostatic, hydrophobic, or click chemistry-based linking

05Rapid Turnaround & Responsive Support

Fast project initiation and transparent project tracking

06Customizable for Research or GMP Use

R&D-scale and GMP-grade options available for preclinical and clinical pipelines

From Concept to Custom Delivery Platform - Step-by-Step Support

1Project Consultation & Requirement Analysis

Understand target type (e.g., tumor cells, receptors, tissues)

Define delivery goals: small molecule, RNA, protein, etc.

Choose appropriate delivery route and formulation needs

2Targeting Peptide Design & Optimization

Custom peptide ligand design based on target

Structural modeling, sequence tuning, and modifications

3Carrier Selection & Functionalization

Recommend optimal nanocarrier (LNP, polymer, exosome, etc.)

Peptide-to-carrier conjugation strategy and formulation design

4Peptide Synthesis & Carrier Fabrication

Peptide synthesis with analytical QC

Nanocarrier formulation with or without payload encapsulation

5System Characterization & Validation

Particle size, zeta potential, encapsulation efficiency

In vitro targeting and uptake evaluation (optional)

6Scale-up & Documentation

Scale-up under R&D or GMP conditions (upon request)

Provide analytical reports, formulation protocol, and QC results

7Packaging & Global Delivery

Secure packaging under required storage conditions

Worldwide shipping with full documentation support

Application Areas of Targeted Delivery System

Empowering Drug Discovery, Gene Therapy, and Diagnostics

Targeted Cancer Therapy

Tumor-homing peptides guiding drug-loaded nanoparticles to tumors

mRNA and RNAi Delivery

Targeted LNP or polymer carriers for siRNA, mRNA, or CRISPR payloads

CNS Drug Delivery

BBB-penetrating peptides for brain-targeted systems

Peptide-Antibody Co-Delivery Systems

Dual-targeting strategies for immuno-oncology and autoimmune diseases

Diagnostic Imaging

Peptide-guided contrast agents or fluorescent probes for molecular imaging

Anti-infective Therapies

Targeted antimicrobial peptides or payloads directed at pathogens or infected cells

Personalized Nanomedicine

Ligand-guided delivery platforms for patient-specific molecular profiles

FAQ

1. What types of delivery carriers can you customize with targeting peptides?

2. Can I provide my own peptide sequence or carrier platform for conjugation?

Yes. We support both full-service projects and collaborative models. You can provide your own peptide, nanoparticle formulation, or both-we'll assist with conjugation, optimization, and characterization as needed.

3. What kind of targeting ligands can you design?

We specialize in rational design and synthesis of custom peptides targeting tumor markers, cell surface receptors (e.g., integrins, transferrin receptor, EGFR), tissues (e.g., liver, brain), or disease-specific microenvironments (e.g., acidic pH, enzymes).

4. Do you offer cell-penetrating peptide (CPP) systems?

Absolutely. We can integrate CPPs like TAT, Penetratin, Transportan, or custom-designed CPPs into your delivery system to facilitate intracellular or nuclear delivery.

5. Can you assist with in vitro or in vivo testing of targeting efficiency?

We provide optional in vitro testing services such as cellular uptake assays, FACS analysis, and confocal imaging. In vivo studies may be supported through CRO partners or client collaboration.

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