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At present, the number of endogenous and exogenous bioactive peptides under study is rapidly increasing, and most of these peptides are easily to be degraded by enzymes, which will greatly reduce the therapeutic effect. These peptides can usually be converted to more resistant molecules by making the necessary modifications.
Unusual amino acids are not naturally encoded amino acids. They can be naturally produced by post-translation of plants or bacteria, or chemically synthesized. Peptides modified by these amino acids tend to exhibit unique biological activities and are often included in therapeutic peptide ligands to provide pharmacological activity and potency of the peptides.
Creative Peptides provides the unusual amino acids modified peptides are:
Creative Peptides provides a complete range of unusual amino acid peptide modification services, and we also can provide customers with special amino acid synthesis to meet your specific needs for modification. Every step of peptide synthesis is subject to Creative Peptides’ stringent quality control. Typical delivery specifications include: Reference
Creative Peptides has accumulated a huge library of peptide knowledge including frontier peptide articles, application of peptides, useful tools, and more!
Figure 1. The structural formula of montirelinMontirelin, an analog of thyrotrophin-releasing hormone (TRH) is m ...
Iron chelating agent is a new type of iron-removing treatment based on the combination of directional and in viv ...
NF-кB activator 1, named Act1, is a 60-kDa (574-aa) polypeptide. Based on its interaction with IKKγ, Act1can be ...
(d(CH2)51,Tyr(Me)2,Arg8)-vasopressin, a kind of vasopressin, is a prohormone in neurons in the hypothalamus. Vas ...
Palmitoyl Tripeptide-38, named MATRIXYL synthe'6 and Volulip, a cosmetic peptide or double-oxidized lipopeptide, ...