Creative Peptides has launched a novel ICDSTM-NH2-kit. It could be used to facilitate the transfer of peptides or proteins as well as antibodies across cellular membranes in the cell-based assay.
Therapeutic protein drugs are an important class of medicines most in need of novel therapies. Recently approved recombinant protein therapeutics have been developed to treat a wide variety of clinical indications, including cancers, autoimmunity/inflammation, exposure to infectious agents, and genetic disorders. However, the failure of proteins to penetrate mammalian cells or target tumor cells restricts their value as therapeutic tools in a variety of diseases. Unlike small molecules, a peptide or a protein is normally difficult enter into intact cells due to the cell membrane's semipermeability nature.
Creative Peptides offer ICDSTM-NH2-kit containing good carriers that can easily cross cell membranes. ICDSTM-NH2-kit considered as useful tools to assist the transshipment of peptide or protein from outside to the inside of cells. It provides a convenient way to deliver your bioactive proteins into cells by conjugating them with ICDSTM peptides. This ICDSTM-NH2-kit can be used with a wide range of molecule up to 150kDa. In order to verify its effectiveness, Creative Peptides’ scientists have tested ICDSTM-NH2-kit using a wide variety type of cells, such as SkBr3, HEK293 and CHO, and nearly all of the tests have the positive results.
ICDSTM-NH2-kit mainly composed of ICDSTM peptides and linker, can assemble your protein with ICDSTM peptides to form a conjugate which can flexible transfer across the cell membrane. ICDSTM-NH2-kit is highly and specifically adaptable to many possible applications, giving your research great advantages.
| CAT# | Product Name | Kit Contents | Storage | Protocols |
| ICDS001 | ICDSTM-NH2-kit | ICDSTM peptides: 1 mg. ICDSTM Linker: 2 mg. Buffer: PBS solution (5 mL) Filtration Tube: 2 tubes | 4 ℃ | User Guide: ICDSTM-NH2-kit protocal |
If you foresee a possible future use for your research in a clinical setting, we can help. Contact us to customize your ICDSTM service today!
The ICDS™-NH2-kit is a novel tool designed to assist in the delivery of peptides, proteins, and antibodies across cellular membranes. It uses ICDS™ peptides conjugated with proteins to enable efficient transshipment into cells, facilitating research applications involving large biomolecules up to 150kDa.
The ICDS™-NH2-kit is capable of delivering a wide range of molecules, including peptides, proteins, and antibodies, with a molecular weight up to 150kDa, making it versatile for various research applications across different cell types.
Creative Peptides has tested the ICDS™-NH2-kit on several cell types, including SkBr3, HEK293, and CHO cells. In nearly all tests, the ICDS™-NH2-kit demonstrated positive results, proving its efficacy in cell-based assays.
The ICDS™-NH2-kit uses ICDS™ peptides and a linker to form a conjugate with your protein or peptide, which can then cross the cell membrane. This process allows bioactive molecules to be efficiently delivered into cells, expanding research possibilities in cell-based applications.
The ICDS™-NH2-kit should be stored at 4°C. The protocol involves mixing the linker with your protein sample, followed by several rounds of centrifugation and incubation with ICDS™ peptides. A detailed user guide is provided for easy implementation of the protocol.
