* Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).
The recognition by Hofmeister and Emil Fischer that the structure of proteins is best represented by chains of amino-acids linked to each other through amide bond was preceded by the syntheses of the first simple peptide derivatives by Curtius and later by Fischer. With the discovery of biologically active peptides, the objectives of synthesis underwent a dramatic change. As the pharmaceutical industry develops rapidly, peptide synthesis becomes more widespread.
Fig1. Peptide synthesis has proven to be useful for several applications.
Before any meaningful studies about proteins and peptides can be performed, it is important to consider several factors. The length of sequence, amino acid residues and the sequence of peptides will influence whether correct assembly and purification are feasible. So we need some strategies to design peptide better.
Peptide synthesis is generally divided into two types: solid phase synthesis and liquid phase synthesis. Specifically, the solid phase synthesis method has become a kind of common technique in the synthesis of peptides and proteins, which sequence generally synthesized from the N-terminus (amino terminus) to the C-terminus (carboxy terminus).
We have the capacity and capability to produce GMP peptides, APIs in annual quantities of hundreds of kilograms. Creative Peptides' GMP production sites were designed in strict accordance to US-FDA guidelines for GMP Manufacturing.
We can assist customers in selecting the appropriate peptide sequence, purity and quantity suitable for your needs. Each step of peptide synthesis is subject to Creative Peptides' stringent quality control. Typical delivery specifications include:
References
Creative Peptides has accumulated a huge library of peptide knowledge including frontier peptide articles, application of peptides, useful tools, and more!
MEN 10376 (Asp-Tyr-D-Trp-Val-D-Trp-D-Trp-Lys-NH2) is an analogue of Neurokinin A (NKA), which has a selective af ...
Timonacic's chemical name, L-Syrosin-4, is a new anti-tumor drug that converts cancer cells into normal cells. E ...
Acetyl pepstatin, nature products of yeast fermentation, is general inhibitors of the family of aspartic proteas ...
Antazoline is a drug used in the treatment of atrial fibrillation (AF), and its formula is C17H19N3. In fact, th ...
Margatoxin (MgTX) is a 39 amino acid peptide with significant sequence homology to charybdotoxin (ChTX), and ha ...