Targeting Peptide Custom Services
Targeting Peptide ServicesTailored Peptide Development
Targeting Peptides are a class of functional short peptides capable of specifically recognizing and binding to certain cells, receptors, or tissues. They are widely used in targeted drug delivery, imaging probe construction, blood-brain barrier (BBB) transport, as well as disease-related research such as tumors and inflammation.
Creative Peptides leverages advanced peptide synthesis platforms and molecular modification technologies to provide one-stop targeting peptide services, covering sequence design, custom synthesis, functional modification, carrier conjugation, and targeting validation. We help clients rapidly advance various projects from basic research to preclinical development. We support custom synthesis of classic targeting peptides such as RGD, NGR, T7, Angiopep, and can also design target-specific peptides and construct peptide libraries according to client needs. These peptides are widely applied in anti-tumor, BBB crossing, inflammation localization, targeted imaging, and other research areas. Our services support gram-scale synthesis, high-purity purification, and strict quality control, suitable for small-scale to scale-up R&D phases.
Our Targeting Peptide Custom Services
01Provides various structural forms including linear peptides, cyclic peptides, and multi-branched peptides
High purity synthesis, supporting GMP-grade customization
Fast delivery turnaround
03Peptide sequence recommendations based on disease or target (e.g., brain-targeting Angiopep-2)
Provides in vitro binding affinity modeling, literature comparison, and optimization suggestions
Supports peptide library design and synthesis screening platform setup
04HPLC purification, LC-MS qualitative analysis, MALDI-TOF quantitative analysis
Standard COA reports meeting regulatory filing or publication requirements
Providing impurity profiling and stability testing according to project needs
05Construction of targeting peptide-LNP/liposome/polymer nanoparticle complexes
Particle size, charge, encapsulation efficiency testing
Optional support with in vitro uptake or in vivo distribution data
Why Choose Us? - Key Advantages of Our Targeting Peptide Services
01Highly Professional
Experienced peptide chemistry team specializing in tumor, brain-targeting, and immune-related targeting peptides.
02Flexible Customization
Comprehensive customization from sequence design to functional modification, meeting needs from basic research to preclinical development.
03Rich Modification Options
Over 30 types of functional modifications available, including biotin, FITC, Cy5, fatty acids, PEG, linker design, etc.
04High-Purity Delivery
Multi-step purification ensures purity ≥95%, supported by professional QC reports such as NMR, LC-MS, AAA.
From Sequence to Delivery - One-Stop Targeting Peptide Service Workflow
1Requirement Communication
Clients submit target information or intended applications; we evaluate and provide technical advice.
2Targeting Peptide Design/Confirmation
We offer literature-supported peptide sequence suggestions or accept sequences directly provided by clients.
3Synthesis and Modification
Peptides are synthesized using automated platforms, with options for fluorescent labeling, biotinylation, PEGylation, and more.
4Purification and Quality Control Analysis
Purification and analysis are performed using HPLC, LC-MS, etc., to ensure high-quality delivery.
5Delivery and Technical Support
We provide COA, analytical reports, and lyophilized samples, with ongoing support for conjugation or delivery system development.
Application Areas of Targeting Peptides
Targeting Peptides play a crucial role in various biomedical and pharmaceutical fields due to their ability to specifically bind to cells, receptors, or tissues. Key application areas include:
Targeted Drug Delivery
Enhancing the precision and efficacy of therapeutic agents by directing drugs specifically to diseased cells or tissues, minimizing off-target effects.
Molecular Imaging and Diagnostics
Serving as molecular probes for imaging modalities such as PET, MRI, and fluorescence imaging to visualize disease biomarkers and monitor treatment response.
Crossing Biological Barriers
Facilitating the transport of therapeutic molecules across challenging biological barriers, such as the blood-brain barrier, enabling treatment of central nervous system disorders.
Cancer Therapy
Targeting tumor-specific markers to improve the selectivity and potency of anti-cancer drugs and immunotherapies.
Inflammation and Immune Modulation
Directing therapeutics to inflammatory sites or immune cells to modulate immune responses in autoimmune diseases and chronic inflammation.
Nanoparticle Functionalization
Decorating nanoparticles, liposomes, or other drug carriers with Targeting Peptides to improve targeting specificity and delivery efficiency.
FAQ
1. What are targeting peptides? What are their main applications?
Targeting peptides are short peptide sequences that specifically recognize and bind to particular cells, tissues, or receptors. They are commonly used in tumor-targeted drug delivery, blood-brain barrier transport, targeted imaging, biomarker recognition, and nanocarrier functionalization research.
2. Can I provide my own targeting peptide sequence, or can you help design one?
We support client-provided sequences as well as assist with screening and optimizing targeting peptide sequences based on your target, disease type, or application. We also recommend validated classical peptides such as RGD, NGR, T7, Angiopep, or novel candidate sequences.
3. What types of targeting peptide modifications do you offer?
We provide a variety of modification services including but not limited to fluorescent labeling (FITC, Cy3, Cy5), biotinylation, fatty acid modification, PEGylation, linker introduction, cyclization, and D-amino acid substitution. These support subsequent conjugation with drugs, oligonucleotides, or nanomaterials.
4. How do you ensure the purity and quality of targeting peptides?
All targeting peptides undergo HPLC purification and rigorous quality testing via LC-MS, MALDI-TOF, and more. We provide complete COA reports and can offer additional analyses such as NMR, AAA, SEC upon request.
5. Do you provide targeting peptide-LNP or carrier functionalization services?
Yes, we offer conjugation and modification services for targeting peptides with lipid nanoparticles (LNP), liposomes, polymer nanoparticles, protein nanocages, and other carriers to build targeted delivery systems.
