Targeting Peptide ServicesTailored Peptide Development
Targeting Peptides are a class of functional short peptides capable of specifically recognizing and binding to certain cells, receptors, or tissues. They are widely used in targeted drug delivery, imaging probe construction, blood-brain barrier (BBB) transport, as well as disease-related research such as tumors and inflammation.
Creative Peptides leverages advanced peptide synthesis platforms and molecular modification technologies to provide one-stop targeting peptide services, covering sequence design, custom synthesis, functional modification, carrier conjugation, and targeting validation. We help clients rapidly advance various projects from basic research to preclinical development. We support custom synthesis of classic targeting peptides such as RGD, NGR, T7, Angiopep, and can also design target-specific peptides and construct peptide libraries according to client needs. These peptides are widely applied in anti-tumor, BBB crossing, inflammation localization, targeted imaging, and other research areas. Our services support gram-scale synthesis, high-purity purification, and strict quality control, suitable for small-scale to scale-up R&D phases.
Provides various structural forms including linear peptides, cyclic peptides, and multi-branched peptides
High purity synthesis, supporting GMP-grade customization
Fast delivery turnaround
Biotinylation, fluorescent labeling, PEGylation, lipidation, bifunctional modifications
Supports Click Chemistry site design and drug linker introduction
Enables conjugation of peptide-drug, peptide-oligonucleotide, and peptide-nanomaterial
Peptide sequence recommendations based on disease or target (e.g., brain-targeting Angiopep-2)
Provides in vitro binding affinity modeling, literature comparison, and optimization suggestions
Supports peptide library design and synthesis screening platform setup
HPLC purification, LC-MS qualitative analysis, MALDI-TOF quantitative analysis
Standard COA reports meeting regulatory filing or publication requirements
Providing impurity profiling and stability testing according to project needs
Construction of targeting peptide-LNP/liposome/polymer nanoparticle complexes
Particle size, charge, encapsulation efficiency testing
Optional support with in vitro uptake or in vivo distribution data
Highly Professional
Experienced peptide chemistry team specializing in tumor, brain-targeting, and immune-related targeting peptides.
Flexible Customization
Comprehensive customization from sequence design to functional modification, meeting needs from basic research to preclinical development.
Rich Modification Options
Over 30 types of functional modifications available, including biotin, FITC, Cy5, fatty acids, PEG, linker design, etc.
High-Purity Delivery
Multi-step purification ensures purity ≥95%, supported by professional QC reports such as NMR, LC-MS, AAA.
Clients submit target information or intended applications; we evaluate and provide technical advice.
We offer literature-supported peptide sequence suggestions or accept sequences directly provided by clients.
Peptides are synthesized using automated platforms, with options for fluorescent labeling, biotinylation, PEGylation, and more.
Purification and analysis are performed using HPLC, LC-MS, etc., to ensure high-quality delivery.
We provide COA, analytical reports, and lyophilized samples, with ongoing support for conjugation or delivery system development.
Targeting Peptides play a crucial role in various biomedical and pharmaceutical fields due to their ability to specifically bind to cells, receptors, or tissues. Key application areas include:
Enhancing the precision and efficacy of therapeutic agents by directing drugs specifically to diseased cells or tissues, minimizing off-target effects.
Serving as molecular probes for imaging modalities such as PET, MRI, and fluorescence imaging to visualize disease biomarkers and monitor treatment response.
Facilitating the transport of therapeutic molecules across challenging biological barriers, such as the blood-brain barrier, enabling treatment of central nervous system disorders.
Targeting tumor-specific markers to improve the selectivity and potency of anti-cancer drugs and immunotherapies.
Directing therapeutics to inflammatory sites or immune cells to modulate immune responses in autoimmune diseases and chronic inflammation.
Decorating nanoparticles, liposomes, or other drug carriers with Targeting Peptides to improve targeting specificity and delivery efficiency.
Targeting peptides are short peptide sequences that specifically recognize and bind to particular cells, tissues, or receptors. They are commonly used in tumor-targeted drug delivery, blood-brain barrier transport, targeted imaging, biomarker recognition, and nanocarrier functionalization research.
We support client-provided sequences as well as assist with screening and optimizing targeting peptide sequences based on your target, disease type, or application. We also recommend validated classical peptides such as RGD, NGR, T7, Angiopep, or novel candidate sequences.
We provide a variety of modification services including but not limited to fluorescent labeling (FITC, Cy3, Cy5), biotinylation, fatty acid modification, PEGylation, linker introduction, cyclization, and D-amino acid substitution. These support subsequent conjugation with drugs, oligonucleotides, or nanomaterials.
All targeting peptides undergo HPLC purification and rigorous quality testing via LC-MS, MALDI-TOF, and more. We provide complete COA reports and can offer additional analyses such as NMR, AAA, SEC upon request.
Yes, we offer conjugation and modification services for targeting peptides with lipid nanoparticles (LNP), liposomes, polymer nanoparticles, protein nanocages, and other carriers to build targeted delivery systems.
