* Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).
Cross-linking refers to the process of chemically bonding two or more molecules through a covalent bond. The crosslinker comprises a reactive end which is reactive with specific functional groups located on proteins or other molecules, such as primary amines and sulfhydryl groups. Multiple chemical groups on proteins and polypeptides can be used for cross-linking, so proteins and polypeptides can be used as targets for coupling in studies using cross-linking methods.
Cross-linkers are used to determine the relationship between adjacent proteins as well as ligand-receptor interactions. Photo-reactive crosslinkers are widely used for nonspecific bioconjugation. While numerous options exist, the two most common photo-reactive chemical groups are diazirines and aryl-azides. Photo cross linkers are used for the study of protein-protein or protein-oligonucleotide interactions in living cells. They are typically used in the following manner:
Creative Peptides is committed in exploiting new technologies and providing comprehensive peptides modification and conjugation services to help our clients with various projects, please contact us for more information and a detailed quote. We have advanced technical support, strong comprehensive strength, rich quality management experience, and huge scale effect. Creative Peptides provides high-quality, low-cost, high-tech peptide products to customers around the world. Every step of peptide synthesis is subject to Creative Peptides’ stringent quality control. Typical delivery specifications include:
References
Creative Peptides has accumulated a huge library of peptide knowledge including frontier peptide articles, application of peptides, useful tools, and more!
Acetyl pepstatin, nature products of yeast fermentation, is general inhibitors of the family of aspartic proteas ...
Anisomycin, also known by its trade name flagecidin, is a bacterial pyrrolidine antibiotic mostly isolated from ...
Acid-sensitive ion channels (ASICs) are a class of proton-gated ion channels belonging to the Degenerin/Epitheli ...
Huwentoxin IV, a 35-amino-acid-residue polypeptide from Chinese tarantula Ornithoctonus huwena venom, is a kind ...
Gap 19 is a nonapeptide derived from the cytoplasmic loop (CL) of Connexin-43 (Cx43). Cx43 is a predominant card ...