Goserelin Acetate
Goserelin acetate stimulates the production of the sex hormones testosterone and estrogen in a non-pulsatile (non-physiological) manner. This causes the disruption of the endogenous hormonal feedback systems, resulting in the down-regulation of testosterone and estrogen production.
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| CAT# | 10-101-20 |
| Chemical Structure |  |
| CAS | 145781-92-6 |
| Synonyms/Alias | (D-Ser(tBu)6; Azagly10)-LHRH; goserelin; Zoladex; Decapeptide I; Goserelin acetate; Gosereline; Goserelinum; Goserelina; Goserelin; ICI 118630; ICI-118630; ICI118630 |
| M.F/Formula | C59H84N18O14 |
| M.W/Mr. | 1269.43 |
| Sequence | Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2 acetate salt |
| Application | Goserelin acetate is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis. |
| Areas of Interest | Cancer Research, Pituitary & Hypothalamic Hormones, Veterinary Medicine |
| Source# | Synthetic |
Long-term Storage Conditions | −20°C |
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