Protease-Activated Receptor-2, amide (SLIGKV-NH2) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.
CAT# | R1637 |
Chemical Structure | |
CAS | 190383-13-2 |
Synonyms/Alias | Thrombin Receptor-Like 1 (1-6) amide (human), SLIGKVamide, Proteinase Activated Receptor 2 (1-6) amide (human), Coagulation Factor II Receptor-Like 1 (1-6) amide (human) |
M.F/Formula | C28H54N8O7 |
M.W/Mr. | 619.68 |
Sequence | One Letter Code: SLIGKV-NH2 three Letter Code: Ser-Leu-Ile-Gly-Lys-Val-NH2 |
Biological Activity | Protease-activated receptor 2 (PAR2) agonist (Ki = 9.64 μM and IC50 = 10.4 μM). Corresponds to the tethered ligand exposed by trypsin cleavage of PAR-2. |
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