R8-T198wt, derived from p27Kip1, is cell-permeable peptide inhibitor of Pim-1 kinase. It Inhibits Pim-1 phosphorylation of p27Kip1 and Bad, and induces cell cycle arrest (at G1) and apoptosis in DU145 prostate cancer cells. It is primarily used for Cancer applications.
CAT# | R0863 |
M.F/Formula | C111H211N59O26S |
M.W/Mr. | 2820.33 |
Sequence | GGGRRRRRRRRGCKKPGLRRRQT |
Labeling Target | PIM Kinase |
Appearance | White solid |
Purity | >95% |
Activity | Inhibitor |
Areas of Interest | Cancer |
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