Adrenorphin

    Adrenorphin is widely distributed throughout the mammalian brain. It has strong opioid activity, can be used as an effective agonist of μ opioid receptors, and has analgesic and respiratory depression effects. Ki is 12 nM.

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    Adrenorphin(CAS 88377-68-8)

    CAT No: R1816

    CAS No: 88377-68-8

    Quick InquiryCustom Peptide Synthesis

    cGMP Peptide

    Registration of APIs CMC information required for an IND

    IND and NDA support Drug master files (DMF) filing

    Specification Technical Data Publications Customer reviews and Q&A
    Synonyms/Aliasadrenorphin;Metorphamide;88377-68-8;HY-P1087;MFCD00065523;Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2;DA-65420;MS-31834;H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2;CS-0027637;Metorphamide; Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2;(S)-N-((S)-1-amino-3-methyl-1-oxobutan-2-yl)-2-((2S,5S,8S,17S)-17-amino-8-benzyl-2-(3-guanidinopropyl)-18-(4-hydroxyphenyl)-5-(2-(methylthio)ethyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaoctadecanamido)-5-guanidinopentanamide;
    M.F/FormulaC44H69N15O9S
    M.W/Mr.984.2
    SequenceOne Letter Code:YGGFMRRV
    Three Letter Code:H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2
    AppearancePowder
    Purity> 95%
    Long-term Storage ConditionsDMSO : 50 mg/mL (50.80 mM; Need ultrasonic)
    Shipping ConditionShip with RT , or blue ice upon request
    InChIInChI=1S/C44H69N15O9S/c1-25(2)36(37(46)63)59-41(67)31(12-8-19-52-44(49)50)57-39(65)30(11-7-18-51-43(47)48)56-40(66)32(17-20-69-3)58-42(68)33(22-26-9-5-4-6-10-26)55-35(62)24-53-34(61)23-54-38(64)29(45)21-27-13-15-28(60)16-14-27/h4-6,9-10,13-16,25,29-33,36,60H,7-8,11-12,17-24,45H2,1-3H3,(H2,46,63)(H,53,61)(H,54,64)(H,55,62)(H,56,66)(H,57,65)(H,58,68)(H,59,67)(H4,47,48,51)(H4,49,50,52)/t29-,30-,31-,32-,33-,36-/m0/s1
    InChI KeyXJOQRTJDYAHKPY-MWSMAVIUSA-N
    Canonical SMILESCC(C)C(C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCSC)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N

    1. Identification, Localization in the Central Nervous System and Novel Myostimulatory Effect of Allatostatins in Tenebrio molitor Beetle

    2. Effect of Short-Term Desiccation, Recovery Time, and CAPA-PVK Neuropeptide on the Immune System of the Burying Beetle Nicrophorus vespilloides

    3. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis

    4. Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

    5. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy

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