Adrenorphin

Adrenorphin is widely distributed throughout the mammalian brain. It has strong opioid activity, can be used as an effective agonist of μ opioid receptors, and has analgesic and respiratory depression effects. Ki is 12 nM.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Adrenorphin(CAS 88377-68-8)

CAT No: R1816

CAS No:88377-68-8

Synonyms/Alias:adrenorphin;Metorphamide;88377-68-8;HY-P1087;MFCD00065523;Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2;DA-65420;MS-31834;H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2;CS-0027637;Metorphamide; Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2;(S)-N-((S)-1-amino-3-methyl-1-oxobutan-2-yl)-2-((2S,5S,8S,17S)-17-amino-8-benzyl-2-(3-guanidinopropyl)-18-(4-hydroxyphenyl)-5-(2-(methylthio)ethyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaoctadecanamido)-5-guanidinopentanamide;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C44H69N15O9S
M.W/Mr.
984.2
Sequence
One Letter Code:YGGFMRRV
Three Letter Code:H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2
Appearance
Powder
Purity
> 95%
Long-term Storage Conditions
DMSO : 50 mg/mL (50.80 mM; Need ultrasonic)
Shipping Condition
Ship with RT , or blue ice upon request
InChI
InChI=1S/C44H69N15O9S/c1-25(2)36(37(46)63)59-41(67)31(12-8-19-52-44(49)50)57-39(65)30(11-7-18-51-43(47)48)56-40(66)32(17-20-69-3)58-42(68)33(22-26-9-5-4-6-10-26)55-35(62)24-53-34(61)23-54-38(64)29(45)21-27-13-15-28(60)16-14-27/h4-6,9-10,13-16,25,29-33,36,60H,7-8,11-12,17-24,45H2,1-3H3,(H2,46,63)(H,53,61)(H,54,64)(H,55,62)(H,56,66)(H,57,65)(H,58,68)(H,59,67)(H4,47,48,51)(H4,49,50,52)/t29-,30-,31-,32-,33-,36-/m0/s1
InChI Key
XJOQRTJDYAHKPY-MWSMAVIUSA-N
Canonical SMILES
CC(C)C(C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCSC)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N

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