Thymosin β4 Acetate

Thymosin β4 is a 43 amino acid peptide which is regarded as the main intracellular G-actin sequestering peptide. Extracellular thymosin β4 may contribute to physiological processes such as angiogenesis, wound healing and regulation of inflammation.

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CAT#10-101-35
CAS77591-33-4 (net)
Background

Thymosin β4 is also called TB-500. It is a protein that in humans is encoded by the TMSB4X gene. And it is a member of the beta thymosin group, of which there are 15 subtypes reported to date. Beta thymosins are a family of proteins which have in common a sequence of about 40 amino acids similar to the small protein thymosin β4. They are found almost exclusively in multicellular animals. Beta thymosins all possess the amino acid sequence 17-LKKTETQEK-25, which serves as an actin binding site. >> Read More

Synonyms/AliasFx Peptide; Thymosin beta4; Thymosin beta 4; Thymosin beta(4); Thymosin β4; Tβ4; Tb4; Thymosin beta-4; Thymosin β-4; Thymosin β 4; TB-500
M.F/FormulaC212H350N56O78S
M.W/Mr.4963.49
SequenceAc-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH
Labeling TargetG-actin monomers
ApplicationThymosin β4 has been tested in multicenter trials in patients with bed sores, ulcers caused by venostasis, epidermolysis bullosa simplex and chronic neurotrophic corneal epithelial defects. And it was found to promote repair.
Biological ActivityThymosin β4 Acetate is a 43 amino acid peptide which is regarded as the main intracellular G-actin sequestering peptide.
Areas of InterestCosmetic Peptides & Dermatology
Inflammation Research
Regenerative Medicine
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