Angiotensin II Acetate

Angiotensin II is an octapeptide that produced from angiotensin I after the removal of two amino acids at the C-terminal by angiotensin-converting enzyme (ACE). Angiotensin II is mediated by AT1 and AT2 receptors, which are seven transmembrane glycoproteins with 30% sequence similarity.

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CAT#10-101-03
CAS4474-91-3 (net)
Synonyms/AliasAngiotensin II; Ang II
Chemical Nameacetic acid;(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(1S)-1-carboxy-2-phenylethyl]carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
M.F/FormulaC52H75N13O14
M.W/Mr.1106.2
SequenceH-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
Labeling TargetAngiotensin Receptor
ApplicationUse as a vasoconstrictor indicated for increasing blood pressure in adults with septic or other distributive shock
AppearanceSolid powder
Purity>98% (or refer to the Certificate of Analysis)
ActivityAn Angiotensin II Type 1 and Type 2 Receptor Agonist.
Areas of InterestCardiovascular Disease
FunctionsProtein heterodimerization activity
TargetType-1 angiotensin II receptor
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