Nafarelin Acetate

Nafarelin acetate is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.

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CAT#10-101-24
CAS76932-56-4 (net)
Synonyms/Alias(D-2-Nal6)-LHRH; RS-94991-298; Synarel; Nafarelinum; Nafarelina; Nafarelin; Nafarelin acetate; LS-88237
M.F/FormulaC10H18N2O7
M.W/Mr.1322.5
SequencePyr-His-Trp-Ser-Tyr-D-2-Nal-Leu-Arg-Pro-Gly-NH2
Labeling TargetGonadotropin-releasing hormone (GNRH) Receptor
ApplicationNafarelin acetate is a potent synthetic agonist of gonadotropin-releasing hormone. Nafarelin has been used in the treatments of central precocious puberty and endometriosis.
AppearanceSolid powder
Purity>98% (or refer to the Certificate of Analysis)
ActivityAgonist
Areas of InterestCardiovascular System & Diseases
Pituitary & Hypothalamic Hormones
FunctionsPeptide binding
DiseaseEndometriosis
Precocious puberty
TargetGonadotropin-releasing hormone (GnRH)
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