Nafarelin Acetate
Nafarelin acetate is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
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| CAT# | 10-101-24 |
| CAS | 76932-56-4 (net) |
| Synonyms/Alias | (D-2-Nal6)-LHRH; RS-94991-298; Synarel; Nafarelinum; Nafarelina; Nafarelin; Nafarelin acetate; LS-88237 |
| M.F/Formula | C10H18N2O7 |
| M.W/Mr. | 1322.5 |
| Sequence | Pyr-His-Trp-Ser-Tyr-D-2-Nal-Leu-Arg-Pro-Gly-NH2 |
| Labeling Target | Gonadotropin-releasing hormone (GNRH) Receptor |
| Application | Nafarelin acetate is a potent synthetic agonist of gonadotropin-releasing hormone. Nafarelin has been used in the treatments of central precocious puberty and endometriosis. |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Activity | Agonist |
| Areas of Interest | Cardiovascular System & Diseases
Pituitary & Hypothalamic Hormones |
| Functions | Peptide binding |
| Disease | Endometriosis
Precocious puberty |
| Target | Gonadotropin-releasing hormone (GnRH) |
| Source# | Synthetic |
Solubility | Soluble in DMSO, not in water |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Short-term Storage Conditions | Dry, dark and at 0 - 4 °C |
Long-term Storage Conditions | -20 °C |
Organism | Human |
BoilingPoint | N/A |
ShelfLife | >2 years if stored properly |
Melting Point | N/A |
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