Fertirelin acetate is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
CAT# | 10-101-17 |
CAS | 38234-21-8 (net) |
Synonyms/Alias | (Des-Gly10,Pro-NHEt9)-LHRH; Fertirelin; Fertirelina; Fertireline; Fertirelinum |
Chemical Name | acetic acid;(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide |
M.F/Formula | C55H74N16O13 |
M.W/Mr. | 1166.56 |
Sequence | One Letter Code: XHWSYGLRP Three Letter Code: H-Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-NHEt.CH3CO2H |
Labeling Target | Gonadotropin-releasing hormone (GNRH) Receptor |
Application | In veterinary medicine fertirelin acetate is used in the treatment of ovarian follicular cysts in cattle and for the improvement of conception rates in cows. |
Activity | Agonist |
Areas of Interest | Pituitary & Hypothalamic Hormones Veterinary Medicine |
Target | Gonadotropin-releasing hormone (GnRH) |
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