Lanreotide Acetate is a somatostatin analog peptide regulating hormone secretion. Purchase Lanreotide peptide online to study tumor suppression and endocrine disorders.
CAT No: R1951
CAS No:127984-74-1
Synonyms/Alias:Lanreotide;Lanreotide acetate;127984-74-1;108736-35-2;10-(4-Aminobutyl)-19-[(2-amino-3-naphthalen-2-yl-propanoyl)amino]-N-(1 -carbamoyl-2-hydroxy-propyl)-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol -3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14, 17-pentazacycloicosane-4-carboxamide;10-(4-aminobutyl)-N-(1-amino-3-hydroxy-1-oxobutan-2-yl)-19-[(2-amino-3-naphthalen-2-ylpropanoyl)amino]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide;Angiopeptin acetate;DC 13-116;3-(2-Naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide cyclic (2-->7)-disulfide;Lanreotide acetate?;Lanreotide acetate salt;SCHEMBL34091;GTPL2031;SCHEMBL14802383;PUDHBTGHUJUUFI-UHFFFAOYSA-N;BDBM627974;CFA98474;DB06791;CVD-0019446;Somatuline; Lanreotidum; BIM 23014C;NCGC00181321-01;BS-42393;DA-54783;DA-54784;EN300-26911522;L000343;(4S,7S,10S,13R,16S,19S)-13-((1H-indol-3-yl)methyl)-19-((R)-2-amino-3-(naphthalen-2-yl)propanamido)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-10-(4-aminobutyl)-16-(4-hydroxybenzyl)-7-isopropyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide acetate;2-({19-[2-amino-3-(naphthalen-2-yl)propanamido]-10-(4-aminobutyl)-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo-7-(propan-2-yl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}formamido)-3-hydroxybutanamide;3-(2-Naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide cyclic (2 inverted exclamation marku7)-disulfide acetate;3-(2-Naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide cyclic (2-->7)-disulfide acetate;Lanreotide; Angiopeptin; 3-(2-Naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide cyclic (2-7)-disulfide; 127984-74-1;
Chemical Name:10-(4-aminobutyl)-N-(1-amino-3-hydroxy-1-oxobutan-2-yl)-19-[(2-amino-3-naphthalen-2-ylpropanoyl)amino]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
Lanreotide Acetate is a synthetic cyclic peptide and a somatostatin analog, structurally designed to mimic the inhibitory actions of natural somatostatin on hormone secretion. As a member of the peptide compound class, it is characterized by its stable structure and high affinity for somatostatin receptors, particularly subtypes 2 and 5. Its unique sequence and conformational properties make it a valuable tool in biochemical research focused on peptide-receptor interactions, signal transduction, and hormone regulation. Researchers utilize Lanreotide Acetate to probe the molecular mechanisms underlying somatostatin-mediated pathways and to explore the modulation of endocrine and neuroendocrine processes in experimental systems.
Receptor Binding Studies: Lanreotide Acetate is frequently employed in receptor binding assays to investigate the affinity and selectivity of somatostatin analogs for various somatostatin receptor subtypes. By radiolabeling or fluorescently tagging the peptide, researchers can quantify binding kinetics, receptor occupancy, and competitive inhibition profiles. These studies are instrumental in mapping receptor distribution in different tissues, elucidating receptor-ligand dynamics, and supporting the development of novel analogs with improved pharmacological properties.
Signal Transduction Research: In cellular and molecular biology laboratories, Lanreotide Acetate serves as a model peptide for dissecting downstream signaling events initiated by somatostatin receptor activation. Experimental models utilize this analog to trigger G-protein coupled receptor pathways, modulate cyclic AMP levels, and influence intracellular calcium flux. Through these investigations, scientists can clarify the roles of specific signaling cascades in hormone secretion, cell proliferation, and neurotransmitter release, thereby enhancing the understanding of fundamental physiological processes.
Endocrine Regulation Studies: The compound is widely used in experimental systems to study the regulation of hormone secretion from endocrine and neuroendocrine cells. By applying Lanreotide Acetate to cultured pituitary, pancreatic, or gastrointestinal cell lines, researchers can observe its effects on the synthesis and release of hormones such as growth hormone, insulin, and glucagon. These studies provide valuable insights into feedback mechanisms, paracrine signaling, and the physiological relevance of somatostatin analogs in endocrine homeostasis.
Peptide Stability and Metabolism Analysis: Lanreotide Acetate is also utilized as a reference peptide in studies examining the stability, degradation, and metabolic fate of cyclic peptides in biological matrices. Its robust structure allows researchers to evaluate proteolytic resistance, identify metabolic breakdown products, and optimize peptide formulation strategies. Such analyses are critical for advancing the design of peptide-based research tools and improving the reliability of experimental outcomes involving peptide compounds.
Peptide Synthesis and Analytical Method Development: The synthetic nature and well-characterized structure of Lanreotide Acetate make it an ideal standard for validating peptide synthesis protocols and analytical techniques. Laboratories utilize it to calibrate chromatographic systems, test purification methods, and assess assay sensitivity for peptide quantification. Its application in these technical contexts supports quality control, method development, and the establishment of reproducible workflows in peptide chemistry research.
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