Angiotensin II human (Angiotensin II) is a vasoconstrictor that mainly acts on the AT1 receptor. Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis.
CAT No: HB00117
CAS No: 68521-88-0
Synonyms/Alias: ANGIOTENSIN II;4474-91-3;Angiotensin II human;Hypertensin;Human angiotensin II;Angiotensin II (human);Ang II;5-L-Isoleucineangiotensin II;Angiotensin II, human;5-Isoleucine-angiotensin II;Angiotensin II (mouse);Giapreza;Asp-Arg-Val-Tyr-Ile-His-Pro-Phe;1-8-Angiotensin I;Ile(5)-angiotensin II;Isoleucine5-angiotensin II;CHEBI:2719;Delivert;angiotensine II;ANG-(1-8)Octapeptide;isoleucine(5)-angiotensin II;UNII-M089EFU921;DRVYIHPF;Ile5-angiotensin II;Angiotensin II, 5-L-isoleucine-;1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide;Angiotensin II (human type);CHEMBL408403;LJPC-501;Angiotensinum II;Angiotensin II acetate salt;L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine;L-Phenylalanine, N-(1-(N-(N-(N-(N-(N2-L-alpha-aspartyl-L-arginyl)-L-valyl)-L-tyrosyl)-L-isoleucyl)-L-histidyl)-L-prolyl)-;N-(1-(N-(N-(N-(N-(N(2)-L-alpha-aspartyl-L-arginyl)-L-valyl)-L-tyrosyl)-L-isoleucyl)-L-histidyl)-L-prolyl)-L-phenylalanine;(2S,5S,8S,11S,14S,17S)-2-((1H-imidazol-5-yl)methyl)-17-amino-5-((S)-sec-butyl)-1-((S)-2-(((S)-1-carboxy-2-phenylethyl)carbamoyl)pyrrolidin-1-yl)-14-(3-((diaminomethylene)amino)propyl)-8-(4-hydroxybenzyl)-11-isopropyl-1,4,7,10,13,16-hexaoxo-3,6,9,12,15-pentaazanonadecan-19-oic acid;(3S)-3-AMINO-3-{[(1S)-4-CARBAMIMIDAMIDO-1-{[(1S)-1-{[(1S)-1-{[(1S,2S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-CARBOXY-2-PHENYLETHYL]CARBAMOYL}PYRROLIDIN-1-YL]-3-(1H-IMIDAZOL-4-YL)-1-OXOPROPAN-2-YL]CARBAMOYL}-2-METHYLBUTYL]CARBAMOYL}-2-(4-HYDROXYPHENYL)ETHYL]CARBAMOYL}-2-METHYLPROPYL]CARBAMOYL}BUTYL]CARBAMOYL}PROPANOIC ACID;Alanine, N-(1-(N-(N-(N-(N-(N2-L-alpha-aspartyl-L-arginyl)-L-valyl)-L-tyrosyl)-L-isoleucyl)-L-histidyl)-L-prolyl)-3-phenyl-, L-;Angiotensinum II (INN-Latin);Angiotensin cento, human;Angiotensina II (INN-Spanish);Angiotensin II, ile(5)-;Angiotensin ii [INN:JAN];Angiotensin 2;Angiotensin-(1-8) Octapeptide;Delivert (TN);C50H71N13O12;Angiotensin II heavy;Angiotensin II (9CI);Angiotensin II (USAN);ANGIOTENSIN II,HUMAN;SCHEMBL1189;Angiotensin II (acetate);Ang II (acetate);DRVYIHPF (acetate);GTPL2504;SCHEMBL9013957;DTXSID4036778;SCHEMBL20502357;CHEBI:48432;C01CX09;DTXSID30196288;CHEBI:131170;ty-10721;M089EFU921;Angiotensin II (human type) (JAN);BDBM50228195;BDBM50236697;HB3488;AKOS016010178;DB11842;FA73187;NCGC00167130-01;DA-70862;HY-13948;NS00074073;Asp1-Arg2-Val3-Tyr4-Ile5-His6-Pro7-Phe8;C02135;C75211;D02014;DRVY-I*-HPF [I*= I(13C6,15N)];EN300-19742056;Q412999;32044-01-2, 4474-91-3 (salt);ANG-(1-8)Octapeptide, Hypertensin, 4474-91-3, Giapreza;Conalbumin (328-332), 1226776-54-0, RVPSL peptide;ProteoMass(TM) Angiotensin II MALDI-MS Standard, vial of 10 nmol;(2S,5S,8S,11S,14S,17S)-2-((1H-imidazol-4-yl)methyl)-17-amino-5-((S)-sec-butyl)-1-((S)-2-(((S)-1-carboxy-2-phenylethyl)carbamoyl)pyrrolidin-1-yl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-isopropyl-1,4,7,10,13,16-hexaoxo-3,6,9,12,15-pentaazanonadecan-19-oic acid;(3S)-3-amino-3-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S,2S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-carboxy-2-phenylethyl]carbamoyl}pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]carbamoyl}-2-methylbutyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}-2-methylpropyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}propanoic acid;L-phenylalanine, L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-;
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M.F/Formula | C50H71N13O12 |
M.W/Mr. | 1046.2 |
Sequence | One Letter Code:DRVYIHPF Three Letter Code:H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH |
Source# | Synthetic |
Shipping Condition | Room temperature in continental US; may vary elsewhere. |
InChI | InChI=1S/C50H71N13O12/c1-5-28(4)41(47(72)59-36(23-31-25-54-26-56-31)48(73)63-20-10-14-38(63)45(70)60-37(49(74)75)22-29-11-7-6-8-12-29)62-44(69)35(21-30-15-17-32(64)18-16-30)58-46(71)40(27(2)3)61-43(68)34(13-9-19-55-50(52)53)57-42(67)33(51)24-39(65)66/h6-8,11-12,15-18,25-28,33-38,40-41,64H,5,9-10,13-14,19-24,51H2,1-4H3,(H,54,56)(H,57,67)(H,58,71)(H,59,72)(H,60,70)(H,61,68)(H,62,69)(H,65,66)(H,74,75)(H4,52,53,55)/t28-,33-,34-,35-,36-,37-,38-,40-,41-/m0/s1 |
InChI Key | CZGUSIXMZVURDU-JZXHSEFVSA-N |
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