Deslorelin Acetate is a potent GnRH analog peptide for fertility control research. Order Deslorelin peptide from a professional peptide supplier for veterinary applications.
CAT No: 10-101-10
CAS No:57773-65-6 (net)
Synonyms/Alias:deslorelin acetate;82318-06-7;Deslorelin (acetate);UNII-679007NR5C;679007NR5C;SUPRELORIN;DTXSID1046683;DTXCID9026683;82318-06-7 (acetate);1642579-30-3;(D-TRP(SUP 6),DES-GLY(SUP 10))-LH-RH ETHYLAMIDE ACETATE;(S)-1-((3S,6S,9S,12S,15R,18S,21S)-3-((1H-imidazol-5-yl)methyl)-6,15-bis((1H-indol-3-yl)methyl)-21-(3-((diaminomethylene)amino)propyl)-12-(4-hydroxybenzyl)-9-(hydroxymethyl)-18-isobutyl-1,4,7,10,13,16,19-heptaoxo-1-((S)-5-oxopyrrolidin-2-yl)-2,5,8,11,14,17,20-heptaazadocosan-22-oyl)-N-ethylpyrrolidine-2-carboxamide acetate;5-OXO-L-PROLYL-L-HISTIDYL-L-TRYPTOPHYL-L-SERYL-L-TYROSYL-D-TRYPTOPHYL-L-LEUCYL-L-ARGINYL-N-ETHYL-L-PROLINAMIDE ACETATE;DESLORELIN ACETATE (EMA EPAR VETERINARY);DESLORELIN ACETATE [EMA EPAR VETERINARY];NCGC00167516-01;Suprelorin F;Bachem 9022 Acetate;SCHEMBL205614;DESLORELIN ACETATE [MI];CHEMBL2357192;DESLORELIN ACETATE [WHO-DD];Tox21_112514;MFCD09842868;AKOS030485982;DESLORELIN ACETATE [GREEN BOOK];FD41614;TS-10606;CAS-82318-06-7;NS00134281;Q27264098;(Des-Gly10,D-Trp6,Pro-NHEt9)-LHRH High acetate salt;Deslorelin acetate 100 microg/mL in Acetonitrile:Methanol;Deslorelin acetate; 1-9-Luteinizing hormone-releasing factor (swine), 6-D-tryptophan-9-(N-ethyl-L-prolinamide)-, acetate (1:?); 6-D-Tryptophan-9-(N-ethyl-L-prolinamide)-10-deglycinamide-luteinizing hormone-releasing factor (pig) acetate (salt); 6-D-Trypto;L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-N-ethyl-,?acetate (1:1);
Chemical Name:acetic acid;(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Deslorelin Acetate is a potent synthetic peptide analog of gonadotropin-releasing hormone (GnRH), designed to modulate the reproductive endocrine system through its agonistic activity. Characterized by its high binding affinity and prolonged half-life compared to native GnRH, Deslorelin Acetate exhibits robust biological activity, making it a valuable tool for research and experimental applications in endocrinology, reproductive biology, and related fields. Its unique mechanism of action involves stimulating the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), followed by a downregulation of gonadotropin secretion with sustained administration. The stability and bioactivity of Deslorelin Acetate enable precise manipulation of hormonal cascades, providing researchers with a versatile compound for in vitro and in vivo investigations.
Reproductive Endocrinology Research: Deslorelin is extensively used in laboratory settings to study the regulation of reproductive hormones and the hypothalamic-pituitary-gonadal axis. By administering the peptide to cell cultures or animal models, scientists can induce controlled surges or suppressions of LH and FSH, thereby elucidating the feedback mechanisms and dynamics of hormone release. This approach is instrumental in advancing the understanding of reproductive physiology, gonadal function, and the molecular pathways underlying fertility and sexual maturation. The ability to modulate hormone levels with precision makes Deslorelin Acetate a cornerstone in experimental endocrinology.
Assisted Reproductive Technologies: In the field of assisted reproduction, Deslorelin Acetate serves as a valuable agent for synchronizing and manipulating ovulation cycles in animal models. Researchers utilize it to induce ovulation or to suppress endogenous gonadotropin release, facilitating controlled studies on follicular development, oocyte maturation, and timing of fertilization. The compound's predictable pharmacological effects allow for reproducible experimental protocols, supporting the refinement of reproductive technologies and the exploration of gamete biology. Its application in these studies contributes to advancements in animal breeding, genetic research, and fertility preservation.
Oncology and Tumor Biology: GnRH analogs like Deslorelin Acetate are important tools in oncology research, particularly for investigating hormone-dependent tumors. By modulating the endocrine environment, Deslorelin enables scientists to study the impact of reduced sex steroid production on tumor growth, progression, and metastasis in preclinical models. This approach aids in unraveling the interactions between hormones and cancer cells, providing insights into tumor biology, resistance mechanisms, and potential therapeutic targets. The peptide's ability to create hypoestrogenic or hypoandrogenic conditions is especially relevant for modeling hormone-responsive cancers.
Veterinary and Comparative Medicine Studies: Deslorelin Acetate finds significant utility in veterinary research, where it is employed to explore reproductive control, contraception, and seasonal breeding patterns in various animal species. Researchers use the compound to investigate the physiological effects of GnRH modulation on reproductive cycles, behavior, and population management. Its efficacy in suppressing or stimulating reproductive activity under controlled conditions makes it a preferred choice for studies involving wildlife, companion animals, and livestock. The insights gained from these investigations inform strategies for animal health, conservation, and breeding management.
Neuroendocrinology and Behavioral Science: The ability of Deslorelin to influence central and peripheral hormone signaling pathways makes it an important reagent in neuroendocrinology and behavioral research. Scientists employ the peptide to dissect the links between hormonal fluctuations and behavioral phenotypes, such as mating, aggression, and social interactions, in animal models. By manipulating GnRH signaling, researchers can probe the neurobiological mechanisms that govern reproductive and social behaviors, contributing to a deeper understanding of brain-endocrine interactions and their evolutionary significance.
Peptide analogs such as Deslorelin Acetate continue to expand the frontiers of biomedical research by enabling targeted modulation of complex physiological systems. The compound's versatility, stability, and well-characterized mode of action make it an indispensable asset for exploring the intricacies of hormonal regulation, reproductive biology, and endocrine-related pathologies. As scientific exploration advances, Deslorelin Acetate remains a key facilitator in unraveling the molecular and systemic mechanisms that define reproductive health, hormone-dependent diseases, and neuroendocrine function across diverse species.
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