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Icatibant

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CAT#
10-101-163
Synonyms/Alias
HOE 140
CAS No.
130308-48-4
Sequence
D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg
M.W/Mr.
1304.52
Molecular Formula
C59H89N19O13S
Source
Synthetic
Application
Approved for use in acute attacks of hereditary angioedema (HAE). Investigated for use/treatment in angioedema, liver disease, and burns and burn infections.
Description
Icatibant (Firazyr) is a synthetic peptidomimetic drug consisting of ten amino acids, and acts as an effective and specific antagonist of bradykinin B2 receptors. It has been approved in the EU for use in hereditary angioedema, and is under investigation for a number of other conditions in which bradykinin is thought to play a significant role.
Areas of Interest
Hereditary angioedema
Storage
-20°C

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