Alarelin Acetate is a high-purity synthetic peptide used in fertility and ovulation research. Buy Alarelin peptide online from a trusted peptide supplier for advanced hormonal studies.
CAT No: 10-101-02
CAS No:79561-22-1
Synonyms/Alias:ALARELIN ACETATE;Alarelin (Acetate);79561-22-1;79561-22-1 (acetate); 148029-26-9 (free base).;(S)-1-((3S,6S,9S,12S,15R,18S,21S)-3-((1H-imidazol-5-yl)methyl)-6-((1H-indol-3-yl)methyl)-21-(3-((diaminomethylene)amino)propyl)-12-(4-hydroxybenzyl)-9-(hydroxymethyl)-18-isobutyl-15-methyl-1,4,7,10,13,16,19-heptaoxo-1-((S)-5-oxopyrrolidin-2-yl)-2,5,8,11,14,17,20-heptaazadocosan-22-oyl)-N-ethylpyrrolidine-2-carboxamide diacetate;Alarelin Acetate?;Alarelin (Acetate) (Standard);ALARELIN ACETATE [WHO-DD];DPWSRXJWCYEGIV-PFHUABGLSA-N;HY-17405R;Alarelin Acetate - Bio-X trade mark;AKOS030526179;CS-1172;FA64933;AS-74852;BA164142;HY-17405;
Chemical Name:acetic acid;(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Alarelin acetate is a synthetic gonadotropin-releasing hormone (GnRH) agonist peptide renowned for its ability to modulate reproductive hormone signaling pathways. Developed through advanced peptide synthesis techniques, Alarelin acetate mimics the natural GnRH, yet exhibits enhanced stability and bioactivity, making it a valuable tool in research settings. Its unique structure allows for precise interaction with GnRH receptors, leading to controlled downstream effects on the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Researchers utilize Alarelin acetate for its reliable performance in experimental protocols that require the modulation of reproductive endocrinology, as well as its compatibility with a variety of in vitro and in vivo models.
Reproductive Physiology Research: Alarelin acetate is extensively employed in the study of reproductive physiology, particularly in elucidating the mechanisms that regulate the hypothalamic-pituitary-gonadal (HPG) axis. By acting as a potent GnRH agonist, this peptide enables scientists to induce or suppress the release of LH and FSH in laboratory animals, allowing for the investigation of gonadal development, ovulation, spermatogenesis, and hormonal feedback loops. This application is pivotal for advancing our understanding of fertility, puberty, and reproductive aging, as well as for developing novel strategies to manipulate reproductive cycles in animal models.
Endocrine Disruption Studies: Synthetic GnRH analogs like Alarelin acetate serve as essential tools for researching the impacts of endocrine-disrupting compounds in environmental and toxicological studies. By providing a controlled means to stimulate or inhibit the HPG axis, researchers can assess how various chemicals interfere with normal hormonal signaling. This approach is critical for identifying environmental contaminants that may affect wildlife reproductive health and for developing risk assessment models based on mechanistic endocrine data.
Animal Breeding Programs: In the context of animal science, Alarelin acetate is frequently utilized to synchronize estrus and induce ovulation in livestock and aquatic species. Its application in these breeding programs enables precise control over reproductive timing, thereby improving the efficiency of artificial insemination and embryo transfer protocols. Such use not only optimizes breeding schedules but also contributes to genetic improvement and population management efforts, particularly in species where reproductive seasonality poses a challenge.
Comparative Endocrinology: The study of Alarelin acetate in non-mammalian species, such as fish and amphibians, has provided valuable insights into the evolutionary conservation and diversity of GnRH signaling pathways. By administering this analog in comparative endocrinology experiments, scientists can dissect the functional roles of GnRH across different taxa, aiding in the identification of species-specific regulatory mechanisms and the development of tailored reproductive management techniques for conservation or aquaculture purposes.
Peptide Drug Development Research: Alarelin acetate also plays a significant role in the early stages of peptide drug development. Its well-characterized pharmacological profile makes it a reference compound for evaluating the efficacy, receptor selectivity, and metabolic stability of novel GnRH analogs. Researchers leverage this peptide in structure-activity relationship studies, formulation testing, and preclinical modeling to advance the design of next-generation therapeutics targeting reproductive hormone pathways.
Basic and translational research initiatives benefit from the versatility and reliability of Alarelin acetate, which continues to drive innovation in reproductive biology, endocrinology, and peptide-based drug discovery. Its broad applicability across multiple scientific disciplines underscores the importance of synthetic GnRH agonists as indispensable tools for advancing our understanding of hormone regulation, reproductive function, and the development of new biotechnological solutions in both academic and industrial settings.
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