K 41498

K-41498 is a highly selective and effective CRF2 receptor antagonist, and it often is used to treat hypertension in rodents.

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CAT#R0912
CAS434938-41-7
Synonyms/AliasD-Phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-L-norleucyl-L-isoleucyl-L-α-glutamyl-L-isoleucyl-L-α-glutamyl-L-lysyl-L-glutaminyl-L-α-glutamyl-L-lysyl-L-α-glutamyl-L-lysyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-alanyl-L-asparaginyl-L-asparaginyl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-α-aspartyl-L-threonyl-L-Isoleucinamide;
M.F/FormulaC162H276N48O46
M.W/Mr.3632.26
SequenceD-Phe-His-Leu-Leu-Arg-Lys-Nle-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2
Labeling TargetCRF2 receptor
Purity>98%
ActivityAntagonist
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