BAX Inhibiting Peptide V5 protects Bax against conformational changes and it also prevents mitochondrial translocation. In vitro analysis prove that peptide V5 prevents apoptosis, mediated by a number of agents including staurosporine, ultraviolet, and anti-cancer drug.
CAT# | R1852 |
CAS | 579492-81-2 |
Synonyms/Alias | BIP-V5 |
Chemical Name | (S)-6-amino-2-((Z)-((S)-2-((Z)-((S)-2-((Z)-(((S)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-yl)(hydroxy)methylene)amino)-1-hydroxy-4-(methylthio)butylidene)amino)-1-hydroxy-4-methylpentylidene)amino)hexanoic acid |
M.F/Formula | C27H50N6O6S |
M.W/Mr. | 586.8 |
Sequence | One Letter Code: VPMLK Three Letter Code: H-Val-Pro-Met-Leu-Lys-OH |
Labeling Target | Apoptosis |
Appearance | Crystalline solid |
Purity | ≥97% (HPLC) |
Activity | Inhibitor |
Areas of Interest | Cancer |
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