ALX 40-4C Trifluoroacetate

Name: ALX 40-4C Trifluoroacetate
Brand: Creative Peptides
SKU: R1183
Availability: MadeToOrder

ALX 40-4C Trifluoroacetate is a small peptide inhibitor of the chemokine receptor CXCR4, inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1; ALX 40-4C Trifluoroacetate also acts as an antagonist of the APJ receptor, with an IC50 of 2.9 μM.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R1183

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C₅₈H₁₁₄F₃N₃₇O₁₂

M.W/Mr.

1578.76

Sequence

One Letter Code: Ac-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-NH2
three Letter Code: Ac-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-NH2

1. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy

2. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

3. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

4. Crystal Structure of BamB from Pseudomonas aeruginosa and Functional Evaluation of Its Conserved Structural Features

5. Implications of ligand-receptor binding kinetics on GLP-1R signalling

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