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ALX 40-4C Trifluoroacetate is a small peptide inhibitor of the chemokine receptor CXCR4, inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1; ALX 40-4C Trifluoroacetate also acts as an antagonist of the APJ receptor, with an IC50 of 2.9 μM.
| CAT# | R1183 |
| M.F/Formula | C₅₈H₁₁₄F₃N₃₇O₁₂ |
| M.W/Mr. | 1578.76 |
| Sequence | One Letter Code: Ac-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-NH2 three Letter Code: Ac-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-d-Arg-NH2 |
| CAT# | Product Name | M.W | Molecular Formula | Inquiry |
|---|---|---|---|---|
| R1833 | MSH release-inhibiting factor | Inquiry | ||
| R1882 | RF 9 | Inquiry | ||
| R0854 | MLCK inhibitor peptide 18 | Inquiry | ||
| R1656 | RGD peptide (GRGDNP) TFA | Inquiry | ||
| R1133 | [Sar9,Met(O2)11]-Substance P | Inquiry |
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