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APIs

Linaclotide

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CAT#
10-101-161
Synonyms/Alias
Linaclotide; Linzess; UNII-N0TXR0XR5X
CAS No.
851199-59-2
Sequence
H–Cys1–Cys–Glu–Tyr–Cys–Cys–Asn–Pro–Ala–Cys–Thr–Gly–Cys–Tyr–OH
(Disulfide bridge: 1-6; 2-10; 5-13)
M.W/Mr.
1526.74
Molecular Formula
C₅₉H₇₉N₁₅O₂₁S₆
COA
Source
Synthetic
Application
Linaclotide  is apeptide agonist of guanylate cyclase 2C. It was approved by the FDA in August 2012 for the treatment in adults of constipation-predominant irritable bowel syndrome (IBS-C) and chronic idiopathic constipation (CIC).
Description
Linaclotide is a 14-amino acid peptide indicated for the treatment of adults with CC and IBS-C; agonist of guanylate cyclase C
Areas of Interest
Constipation-predominant irritable bowel syndrome (IBS-C) and chronic idiopathic constipation (CIC)
Storage
-20°C

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