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The history of the discovery and research of GLP-1 (Glucagon like peptide-1) can be traced back to the late 60s to early 70s of the 20th century. Initially, scientists discovered the hormone while stu
What is GIP? GIP (Gastric Inhibitory Polypeptide or Glucose-dependent Insulinotropic Peptide) is a peptide hormone composed of 42 amino acids secreted by intestinal K cells, mainly produced in the d
Introduction The β-amyloid precursor protein (APP) is connected to Alzheimer's disease by both biochemistry and genetics. As the source of the major constituent of amyloid plaques, APP has been the su
IGF-1 IGF-1 is a single chain peptide consists of 70 amino acids in four domains, B, C, A and D. The A- and B-domains are structural homologs of the insulin A- and B-chains with 50% sequence similarit
Proteolytic Processing of APP Following discovery of the full-length APP cDNA clone, numerous studies were undertaken to detect the APP protein in cells and tissues. Full-length, membrane-bound forms