GLP-1 is a 30 amino acid peptide (molecular weight of 3297.5) secreted by intestinal L-cells in response to meal ingestion with lipids and carbohydrates. GLP-1 exerts its effect by acting on G-protein
GIP is a 42-aminoacid peptide secreted from the intestinal K-cells (located mainly in the duodenum and proximal jejunum) and released in response to nutrients, especially fats. The aminoacid sequence
Introduction The β-amyloid precursor protein (APP) is connected to Alzheimer's disease by both biochemistry and genetics. As the source of the major constituent of amyloid plaques, APP has been the su
IGF-1 IGF-1 is a single chain peptide consists of 70 amino acids in four domains, B, C, A and D. The A- and B-domains are structural homologs of the insulin A- and B-chains with 50% sequence similarit
Proteolytic Processing of APP Following discovery of the full-length APP cDNA clone, numerous studies were undertaken to detect the APP protein in cells and tissues. Full-length, membrane-bound forms
