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Acetyl Dipeptide-3 Aminohexanoate
Acetyl Dipeptide-3 Aminohexanoate is the reaction product of acetic acid and Dipeptide-3 with 6-aminohexanoic acid. It's a new tripeptide discovery that maintains the balance between commensal microbes and pathogens in the skin.
An additional aspect of this invention refers to a cosmetic or pharmaceutical composition which comprises a cosmetically or pharmaceutically effective quantity of at least one compound of the invention, its stereoisomers, mixtures thereof and/or its cosmetically or pharmaceutically acceptable salts, as well as a cosmetically or pharmaceutically effective quantity of at least one extract, which stimulates the synthesis of defensins, for example and not restricted to, extracts or hydrolyzed extracts of Aloe vera, Roast amaranth, Rehmannias radix, arnica, gardenia, carrot, orange, peach, pineapple, mint, gentian, hibiscus flower, walnut flower, pumpkin, peony, quinoa, boldo, sarsaparille, sunflower, elderberry, seaweed, hydrolyzed maize, hydrolyzed soybean or hydrolyzed rice, among others and/or a cosmetically or pharmaceutically effective quantity of at least one synthetic compound, extract or product from a biofermentation process with stimulatory effect on the expression of the defensins, for example and not restricted to, isoleucine and its isomers and derivatives, valine and its isomers and derivatives, calcium and its salts, α-MSH and fragments contained in the sequence of α-MSH amino acids, vitamin A and its derivatives and precursors, vitamin D3 and its derivatives, jasmonic acid, fumaric acid, malic acid, citric acid, ascorbic acid, lactic acid, acetic acid, adipic acid, tartaric acid, cinnamic acid, glutamic acid, succinic acid, inulin, poly-D-glutamic acid, glycine, L-methionine, L-alanine, L-citrulline, lactoprotein, casein, lactoperoxidase, lysozyme, polyphenol, extract of Lactobacillus, extract of fusobacteria or non-photosynthetic and non-fructifying filamentous bacteria, Bodyfensine [INCI: Acetyl Dipeptide-3 Aminohexanoate], among others.
Anton, J. M. G., Montiel, A. V. F., Serraïma, C. C., GONZÁLEZ, R. D., & Puche, J. C. (2017). U.S. Patent No. 9,725,483. Washington, DC: U.S. Patent and Trademark Office.