This statine-based substrate analog, ?-secretase inhibitor P10–P4’ statV, is used in the inhibition of ?-secretase activity from homogenized wild-type mouse cortices and from BACE-purified from human brain.
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M.F/Formula | 1651.9 |
Sequence | One Letter Code: KTEEISEVN-Sta-VAEF (Sta = statine) Three Letter Code: H-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta-Val-Ala-Glu-Phe-OH |
Length | 16 |
References | Sinha, S. et al. Nature 402, 537 (1999). |
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