Palmitoyl Tripeptide-28 is a synthetic peptide composed of three amino acids conjugated with palmitic acid to enhance skin penetration. Widely utilized in cosmetic formulations, it is valued for its role in supporting skin conditioning and improving the appearance of skin texture. Palmitoyl Tripeptide-28 is compatible with a range of topical applications, including creams, serums, and emulsions, and is suitable for global cosmetic regulatory compliance.
CAT No: CPO-005
Mechanism of Action (MOA)
Palmitoyl Tripeptide-28 is a biomimetic signal peptide designed to support skin's extracellular matrix. By mimicking fragments of naturally occurring proteins, it interacts with cell surface receptors to modulate signaling pathways involved in the synthesis of key matrix components, such as collagen. This peptide's palmitoylation enhances its stability and skin penetration, facilitating its role in cellular communication related to matrix maintenance and structural protein expression.
Palmitoyl Tripeptide-28 is suitable for incorporation into a variety of cosmetic formulations.
- Facial serums and concentrates- Moisturizing creams and lotions- Eye contour products- Sheet masks and leave-on treatments- Overnight creams and sleeping packs- Makeup primers and base products
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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
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