ProTx III

A novel selective Nav1.7 channel blocker (IC50 = 2.5 nM). ProTx-III also inhibits Nav1.1, Nav1.2 and Nav1.6 at nanomolar concentrations and does not affects Cav channels and nicotinic acetylcholine receptors.

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CAT#R0972
M.F/FormulaC162H246N52O43S6
M.W/Mr.3802.41
SequenceDCLKFGWKCNPRNDKCCSGLKCGSNHNWCKLHI-NH2(Disulfide bridge: Cys2 and Cys17, Cys9 and Cys22, Cys16 and Cys29)
Labeling TargetNav1.7 channel
AppearanceWhite lyophilized solid
Purity>98%
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