Acetyl Tetrapeptide-9

Acetyl Tetrapeptide-9 is a synthetic peptide composed of four amino acids, designed for use in cosmetic formulations targeting skin appearance and texture. Known for its role in supporting the skin's extracellular matrix, this ingredient is utilized in anti-aging and skin-firming products. It is compatible with a wide range of formulations and is suitable for inclusion in serums, creams, and other topical applications intended for mature or stressed skin.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Acetyl Tetrapeptide-9(CAS 928006-50-2)

CAT No: CPC1620

CAS No:928006-50-2

Synonyms/Alias:Acetyl tetrapeptide-9;928006-50-2;Acetyl tetrapeptide-9(Dermican LS 9837);Dermican;UNII-VMO8OOD3V0;N-Acetyl-gln-asp-val-his;VMO8OOD3V0;LS 9745;LS-9745;DTXSID00239151;L-Histidine, N2-acetyl-L-glutaminyl-L-alpha-Aspartyl-L-valyl-;Acetyl Tetrapeptide-9 (acetate);(2S,5S,8S,11S)-2-((1H-imidazol-4-yl)methyl)-11-(3-amino-3-oxopropyl)-8-(carboxymethyl)-5-isopropyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecanoic acid;(3S)-3-[(2S)-4-carbamoyl-2-acetamidobutanamido]-3-{[(1S)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-2-methylpropyl]carbamoyl}propanoic acid;(3S)-3-[[(2S)-2-acetamido-5-amino-5-oxopentanoyl]amino]-4-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-imidazol-5-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid;Dermican LS 9837;Acetyl tetrapeptide-9?;SCHEMBL21529460;DTXCID20161642;QNZANUZIBYJBIN-XSWJXKHESA-N;(2S,5S,8S,11S)-2-((1H-Imidazol-4-yl)methyl)-11-(3-amino-3-oxopropyl)-8-(carboxymethyl)-5-isopropyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecan-1-oic acid;DMB00650;HY-P3164;Acetyl Tetrapeptide-9 acetate salt;ACETYL TETRAPEPTIDE-9 [INCI];Acetyltetrapeptide-9(DermicanLS9837);AKOS030573453;DA-50137;DS-19817;CS-0166887;C77180;Q27291905;L-HISTIDINE, N2-ACETYL-L-GLUTAMINYL-L-.ALPHA.-ASPARTYL-L-VALYL-;618-875-8;

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C22H33N7O9
M.W/Mr.
539.5
Sequence
One Letter Code:QDVH
Three Letter Code:Ac-Gln-Asp-Val-His-OH
Functions
Acetyl Tetrapeptide-9 promote dermal remodeling and helps achieve compact and plump the skin effect.

Mechanism of Action (MOA)

Acetyl Tetrapeptide-9 is a synthetic signaling peptide designed to interact with skin's extracellular matrix components. It is believed to support the expression of key proteins involved in dermal architecture, such as lumican, by modulating cellular communication pathways. This activity may help optimize the organization and density of collagen fibers, contributing to improved skin structural integrity. Its mechanism centers on biomimetic peptide signaling without altering physiological functions.

Acetyl Tetrapeptide-9 can be incorporated into various cosmetic formulations to enhance product offerings.

- Suitable for use in facial serums and creams
- Can be added to eye contour gels and lotions
- Compatible with anti-aging and moisturizing products
- Applicable in sheet masks and leave-on treatments
- May be included in lightweight emulsions and gels
- Appropriate for daily skincare formulations

INCIName
Acetyl Tetrapeptide-9
InChI
InChI=1S/C22H33N7O9/c1-10(2)18(21(36)28-15(22(37)38)6-12-8-24-9-25-12)29-20(35)14(7-17(32)33)27-19(34)13(26-11(3)30)4-5-16(23)31/h8-10,13-15,18H,4-7H2,1-3H3,(H2,23,31)(H,24,25)(H,26,30)(H,27,34)(H,28,36)(H,29,35)(H,32,33)(H,37,38)/t13-,14-,15-,18-/m0/s1
InChI Key
QNZANUZIBYJBIN-XSWJXKHESA-N
References
DERMICAN

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