α-Gliadin (31-43)

Name: α-Gliadin (31-43)
Brand: Creative Peptides
SKU: G21001
Availability: MadeToOrder

This peptide is derived from gliadin wheat protein residues 31-43. It elicits an innate immune response by upregulating expression of interleukin (IL)-15 and cyclooxygenase (COX)-2. This peptide also promotes expression of CD25 on monocytes and macrophages, expression of CD83 on dendritic cells, and p38 MAP kinase activation. Treatment with this peptide allows immunodominant epitopes (57-68 and 62-75) to induce T-cell activation and enterocyte apoptosis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: G21001

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.W/Mr.

1527.8

Sequence

One Letter Code: LGQQQPFPPQQPY
Three Letter Code: H-Leu-Gly-Gln-Gln-Gln-Pro-Phe-Pro-Pro-Gln-Gln-Pro-Tyr-OH

References

1. Chambers, S. et al. Anal Biochem 292, 301 (2001).
2. Maiuri, L. et al. Lancet 362, 30 (2003).
3. Mamone, G. et al. J Chromatogr B 855, 236 (2007).

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