α-Gliadin (31-43)
This peptide is derived from gliadin wheat protein residues 31-43. It elicits an innate immune response by upregulating expression of interleukin (IL)-15 and cyclooxygenase (COX)-2. This peptide also promotes expression of CD25 on monocytes and macrophages, expression of CD83 on dendritic cells, and p38 MAP kinase activation. Treatment with this peptide allows immunodominant epitopes (57-68 and 62-75) to induce T-cell activation and enterocyte apoptosis.
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| CAT# | G21001 |
| M.W/Mr. | 1527.8 |
| Sequence | One Letter Code: LGQQQPFPPQQPY
Three Letter Code: H-Leu-Gly-Gln-Gln-Gln-Pro-Phe-Pro-Pro-Gln-Gln-Pro-Tyr-OH |
| Storage | -20°C |
References | 1. Chambers, S. et al. Anal Biochem 292, 301 (2001).
2. Maiuri, L. et al. Lancet 362, 30 (2003).
3. Mamone, G. et al. J Chromatogr B 855, 236 (2007). |
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