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β-Endorphin, equine

β-Endorphin, equine is an endogenous opioid peptide with analgesic properties.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
β-Endorphin, equine(CAS 79495-86-6)

CAT No: R1796

CAS No:79495-86-6

Synonyms/Alias:beta-Endorphin, equine;79495-86-6;beta-Endorphin (equine);ss-Endorphin (Equine);END-3756-PI;DA-59360;

Custom Peptide Synthesis
cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C154H248N42O44S
M.W/Mr.
3423.9
Sequence
One Letter Code:YGGFMSSEKSQXPLVXLFKNAXXKNAHKKGQ
Three Letter Code:H-DL-Tyr-Gly-Gly-DL-Phe-DL-Met-DL-Ser-DL-Ser-DL-Glu-DL-Lys-DL-Ser-DL-Gln-DL-xiThr-DL-Pro-DL-Leu-DL-Val-DL-xiThr-DL-Leu-DL-Phe-DL-Lys-DL-Asn-DL-Ala-DL-xiIle-DL-xiIle-DL-Lys-DL-Asn-DL-Ala-DL-His-DL-Lys-DL-Lys-Gly-DL-Gln-OH
Appearance
White or off-white lyophilized powder
Purity
≥98% (HPLC)
Activity
beta-Endorphin, equine is 1.6 times more potent than the human hormone in the mouse tail-flick assay [1].
Source#
Synthetic
Shipping Condition
Shipped at room temperature
InChI
InChI=1S/C154H248N42O44S/c1-16-82(9)123(150(235)181-98(43-28-33-60-159)133(218)185-108(69-116(163)205)138(223)170-84(11)127(212)182-107(68-91-71-165-78-169-91)143(228)177-95(40-25-30-57-156)131(216)174-94(39-24-29-56-155)130(215)168-74-120(209)172-102(154(239)240)50-53-115(162)204)193-151(236)124(83(10)17-2)192-128(213)85(12)171-139(224)109(70-117(164)206)184-132(217)96(41-26-31-58-157)176-142(227)106(67-89-37-22-19-23-38-89)183-140(225)103(63-79(3)4)187-152(237)125(86(13)200)194-149(234)122(81(7)8)191-144(229)104(64-80(5)6)186-148(233)113-44-34-61-196(113)153(238)126(87(14)201)195-137(222)99(49-52-114(161)203)178-145(230)110(75-197)188-134(219)97(42-27-32-59-158)175-135(220)100(51-54-121(210)211)179-146(231)111(76-198)190-147(232)112(77-199)189-136(221)101(55-62-241-15)180-141(226)105(66-88-35-20-18-21-36-88)173-119(208)73-166-118(207)72-167-129(214)93(160)65-90-45-47-92(202)48-46-90/h18-23,35-38,45-48,71,78-87,93-113,122-126,197-202H,16-17,24-34,39-44,49-70,72-77,155-160H2,1-15H3,(H2,161,203)(H2,162,204)(H2,163,205)(H2,164,206)(H,165,169)(H,166,207)(H,167,214)(H,168,215)(H,170,223)(H,171,224)(H,172,209)(H,173,208)(H,174,216)(H,175,220)(H,176,227)(H,177,228)(H,178,230)(H,179,231)(H,180,226)(H,181,235)(H,182,212)(H,183,225)(H,184,217)(H,185,218)(H,186,233)(H,187,237)(H,188,219)(H,189,221)(H,190,232)(H,191,229)(H,192,213)(H,193,236)(H,194,234)(H,195,222)(H,210,211)(H,239,240)
InChI Key
XWZZJSNGTXUROZ-UHFFFAOYSA-N
References
[1]  Li, CH; et al., Int. J. Peptide Protein Res., 18, 242 (1981).

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